Weng Lei-Ming, Wang Xin, Wang Li, Jin Feng
Institute of Genetics and Developmental Biology, Chinese Academy of Science, Beijing 100101, China.
Yi Chuan. 2006 Apr;28(4):486-92.
The physiological manifestation of myopia is error of refraction. The incidence of myopia in Asian population is increasing much more rapidly compared with several decades ago. Most of the people in the relatively developed Chinese cities are developing or have developed myopia. Recently, researches reported six loci related to myopia. Viewing from the modern civilization and development of China, the sharp increase of the size of the population with myopia and the unbalanced change could not be explained only by gene mutation or any model of Mendelian inheritance. The comparison of the disparity of the economic and educational levels between in urban and rural areas showed that the onset of myopia might be influenced by both environmental and genetic factors. Special attention should be paid to myopia now to prevent severe physical problem in the Chinese urban population.
近视的生理表现是屈光不正。与几十年前相比，亚洲人群中近视的发病率增长得要快得多。在中国相对发达的城市中，大多数人正在发展或已经患上了近视。最近，研究报告了六个与近视相关的基因座。从中国的现代文明和发展来看，近视人群数量的急剧增加和不平衡变化不能仅用基因突变或任何孟德尔遗传模型来解释。城乡经济和教育水平差异的比较表明，近视的发生可能受环境和遗传因素的共同影响。现在应特别关注近视问题，以预防中国城市人口出现严重的身体问题。
