Watz Henrik, Bitter-Suermann Stephanie, Kanniess Frank, Magnussen Helgo
Zentrum für Pneumologie und Thoraxchirurgie, Pneumologisches Forschungsinstitut am Krankenhaus Grosshansdorf, Grosshansdorf.
Med Klin (Munich). 2006 Apr 15;101(4):283-92. doi: 10.1007/s00063-006-1036-6.
Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation that is not fully reversible. It is caused by chronic inflammation of the airways and the lung parenchyma. Symptomatic treatment is based on bronchodilatation, which leads to a reduction of hyperinflation and relief of dyspnea. Smoking cessation is the only known causative treatment option. Inhaled corticosteroids (ICS) reduce exacerbations and, potentially, mortality. Future therapies should ameliorate chronic inflammation and thus stop the annual decline of lung function. In face of increasing mortality and morbidity more research is needed.
慢性阻塞性肺疾病（COPD）的特征是气流受限且不完全可逆。它由气道和肺实质的慢性炎症引起。对症治疗基于支气管扩张，这会减少肺过度充气并缓解呼吸困难。戒烟是唯一已知的病因治疗选择。吸入性糖皮质激素（ICS）可减少急性加重，并有可能降低死亡率。未来的治疗应改善慢性炎症，从而阻止肺功能的逐年下降。鉴于死亡率和发病率不断上升，需要更多的研究。
