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[剂量降低的16层多排螺旋计算机断层扫描在支气管镜检查怀疑有血管性气管狭窄儿童中的应用——初步结果]

[Dose-reduced 16-slice multidetector-row spiral computed tomography in children with bronchoscopically suspected vascular tracheal stenosis -- initial results].

作者信息

Honnef D, Wildberger J E, Das M, Hohl C, Mahnken A, Schnöring H, Vázquez-Jiménez J, Günther R W, Staatz G

机构信息

Klinik für Radiologische Diagnostik, Universitätsklinikum der RWTH Aachen.

出版信息

Rofo. 2006 Apr;178(4):425-31. doi: 10.1055/s-2006-926537.

Abstract

PURPOSE

To evaluate the diagnostic accuracy of contrast-enhanced dose-reduced 16-slice multidetector-row CT (MDCT) in newborns and infants with fiberoptic bronchoscopically suspected vascular-induced tracheal stenosis.

MATERIALS AND METHODS

12 children (4 days to 3 years, 1.2 - 13.5 kg body weight) were examined using i. v. contrast-enhanced 16-slice MDCT (SOMATOM Sensation 16, Forchheim, Germany) without breath-hold and under sedation (11/12). All MDCTs were performed with a dose reduction. The beam collimation was 16 x 0.75 mm, except in the case of one child. MPRs along the tracheal axis in the x-, y- and z-directions and volume-rendering-reconstructions (VRTs) were calculated based on a secondary raw data set in addition to conventional axial slices. 2 radiologists used a three-point grade scale to evaluate the image quality, motion, and contrast media artifacts as well as the usefulness of the 2D- and 3D-reconstructions for determining the diagnosis. Statistical analysis was performed on the basis of a Kappa test.

RESULTS

In all cases the cause of the fiberoptic bronchoscopically suspected tracheal stenosis was revealed: compression due to the brachiocephalic trunk (n = 7), double aortic arch (n = 2), lusorian artery (n = 1), vascular compression of the left main bronchus (n = 2). In 3 patients further thoracic anomalies, such as tracheobronchial (n = 2), and vascular (n = 2) and vertebral (n = 1) anomalies were found. The attenuation in the anomalous vessels was 307 +/- 140 HU. The image noise was 9.8 +/- 1.9 HU. The mean dose reduction was 82.7 +/- 3.2 % compared to a standard adult thoracic CT. All examinations were rated as diagnostically good (median 1, range 1, k = 1). 3D images did not show any stair artifacts (median 2, range 1 - 2, k = 1). The image noise was minor to moderate and hardly any motion artifacts were seen (median 1, range 1 - 2, k = 0.8). Contrast media artifacts were rated zero to minor (median 1.5, range 1 - 2, k = 0.676). MPRs (median 1, range 1, k = 1) and VRTs (median 1, range 1, k = 1) were found to be useful for diagnosis. Subsequent vascular surgery was performed on 8 patients.

CONCLUSION

Contrast-enhanced dose-reduced 16-slice MDCT is effective for demonstrating the cause of fiberoptic bronchoscopically suspected vascular-induced tracheal stenosis even in very small and severely ill children despite the small contrast media amount and free breathing.

摘要

目的

评估对比增强型低剂量16层多排螺旋CT(MDCT)对纤维支气管镜检查怀疑血管性气管狭窄的新生儿和婴儿的诊断准确性。

材料与方法

对12名儿童(年龄4天至3岁,体重1.2 - 13.5 kg)进行了静脉注射对比剂增强的16层MDCT检查(西门子SOMATOM Sensation 16,德国福希海姆),检查时未屏气且使用了镇静剂(12例中有11例)。所有MDCT检查均采用了剂量降低技术。除1名儿童外,其余儿童的束流准直为16×0.75 mm。除了常规轴位图像外,还基于二次原始数据集计算了沿气管轴在x、y和z方向的多平面重组(MPR)以及容积再现重建(VRT)。两名放射科医生使用三点分级量表评估图像质量、运动情况、对比剂伪影以及二维和三维重建对确定诊断的有用性。基于Kappa检验进行统计分析。

结果

在所有病例中均揭示了纤维支气管镜检查怀疑的气管狭窄原因:头臂干压迫(n = 7)、双主动脉弓(n = 2)、迷走动脉(n = 1)、左主支气管血管压迫(n = 2)。在3例患者中还发现了其他胸部异常,如气管支气管异常(n = 2)、血管异常(n = 2)和椎体异常(n = 1)。异常血管的衰减为307±140 HU。图像噪声为9.8±1.9 HU。与标准成人胸部CT相比,平均剂量降低了82.7±3.2%。所有检查的诊断评级均为良好(中位数为1,范围为1,kappa值 = 1)。三维图像未显示任何阶梯状伪影(中位数为2,范围为1 - 2,kappa值 = 1)。图像噪声为轻度至中度,几乎未见运动伪影(中位数为1,范围为1 - 2,kappa值 = 0.8)。对比剂伪影评级为零至轻度(中位数为1.5,范围为1 - 2,kappa值 = 0.676)。发现MPR(中位数为1,范围为1,kappa值 = 1)和VRT(中位数为1,范围为1,kappa值 = 1)对诊断有用。8例患者随后接受了血管手术。

结论

即使在非常小且病情严重的儿童中,尽管对比剂用量少且呼吸自由,但对比增强型低剂量16层MDCT对于显示纤维支气管镜检查怀疑的血管性气管狭窄的病因是有效的。

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