Liang Y
Zhonghua Yi Xue Za Zhi. 1991 Aug;71(8):428-30, 30.
A family with high prevalence of leukemia in Fujian, China was investigated and followed-up for 10 years. 7 members of the family had leukemia. Chromosome analyses once had found that three normal members in the family had chromosome abnormalities, and leukemia occurred in two of them 5 and 7 years later respectively. Family tree analysis showed that hereditary defects are in the maternal side. The author believes that hereditary defects play an important role in familial leukemia.
对中国福建一个白血病高发家族进行了调查并随访10年。该家族中有7名成员患有白血病。染色体分析曾发现该家族3名正常成员存在染色体异常,其中两人分别在5年后和7年后患白血病。系谱分析表明遗传缺陷来自母系。作者认为遗传缺陷在家族性白血病中起重要作用。