[冠心病患者超声检查发现的颈动脉粥样硬化改变]
[Carotid atherosclerotic alterations revealed at ultrasonographic examination in patients with coronary heart disease].
作者信息
Mitu F, Mitu Magda, Turiceanu M, Tudorie Camelia, Pandele G I
机构信息
Universitatea de Medicină si Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, Clinica a VI-a Medicală, Spitalul Clinic de Recuperare Iaşi.
出版信息
Rev Med Chir Soc Med Nat Iasi. 2005 Apr-Jun;109(2):236-41.
UNLABELLED
Carotid ultrasound examination is a noninvasive method with large indications in the evaluation of atherosclerotic lesions at cardiac patients. The aims of the study were: the ultrasound assessment of extra cranial carotid system at patients with coronary heart disease; relationship with the cardiovascular risk factors, lipid profile and echocardiographic data.
METHODS
There were studied 47 patients with coronary heart disease (angina, myocardial infarction, ischemic cardiomyopathy, CABG). The evaluation included cardiovascular risk factors, clinical examination, serum lipids and glucose, echocardiographic data. The ultrasound examination of the carotid arteries included the measurement of the diameter and intima-media thickness (IMT) of the common carotid arteries, the presence and location of atherosclerotic plaques and the presence and severity of carotid stenosis.
RESULTS
There was a significant increase of the diameter and IMT with age (p=0.009 respectively p=0.05). Males had a greater medium diameter than women (7.8 +/- 0.9 mm vs. 7.3 +/- 0.8 mm, p=0.04). There was no significant relationship between the cardiovascular risk factors (smoking, arterial hypertension, diabetes mellitus, dyslipidemia) and IMT. The thickness of the interventricular septum (at the echocardiographic examination) correlated with the IMT (p=0.03). All the patients with myocardial infarction revealed carotid atherosclerotic plaques and most of the smokers had carotid plaques (88.9% vs. 44.8%, p=0.03). Patients with carotid plaques were older (60.9 +/- 10.1 vs. 54.8 +/- 6.1, p=0.02).
CONCLUSIONS
The incidence of carotid atherosclerosis increases with age; the carotid diameter is greater at males and older patients; IMT is influenced mainly by age; carotid plaques are present mainly at older patients, at smokers and those with myocardial infarction and can be considered an additional risk factor for vascular
未标注
颈动脉超声检查是一种非侵入性方法，在评估心脏病患者的动脉粥样硬化病变方面有广泛的适应证。本研究的目的是：对冠心病患者进行颅外颈动脉系统的超声评估；与心血管危险因素、血脂谱和超声心动图数据的关系。
方法
研究了47例冠心病患者（心绞痛、心肌梗死、缺血性心肌病、冠状动脉搭桥术）。评估包括心血管危险因素、临床检查、血脂和血糖、超声心动图数据。颈动脉超声检查包括测量颈总动脉的直径和内膜中层厚度（IMT）、动脉粥样硬化斑块的存在和位置以及颈动脉狭窄的存在和严重程度。
结果
直径和IMT随年龄显著增加（分别为p = 0.009和p = 0.05）。男性的平均直径大于女性（7.8±0.9mm对7.3±0.8mm，p = 0.04）。心血管危险因素（吸烟、动脉高血压、糖尿病、血脂异常）与IMT之间无显著关系。室间隔厚度（超声心动图检查时）与IMT相关（p = 0.03）。所有心肌梗死患者均有颈动脉粥样硬化斑块，大多数吸烟者有颈动脉斑块（88.9%对44.8%，p = 0.03）。有颈动脉斑块的患者年龄较大（60.9±10.1对54.8±6.1，p = 0.02）。
结论
颈动脉粥样硬化的发生率随年龄增加；男性和老年患者的颈动脉直径较大；IMT主要受年龄影响；颈动脉斑块主要出现在老年患者、吸烟者和心肌梗死患者中，可被视为血管的一个额外危险因素
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