Suh Kyung-Suk, Yi Nam-Joon, Cho Jai Yong, Kwon Choon Hyuck, Minn Kyung Won, Lee Kuhn Uk
Department of Surgery, Seoul National University, College of Medicine, Seoul, Korea.
Hepatogastroenterology. 2006 Mar-Apr;53(68):253-7.
BACKGROUND/AIMS: Donor extended right hepatectomy, including the middle hepatic vein (MHV) and a part of segment 4 (Sg4), is performed to overcome inadequate graft for large adult recipient as resolving congestion of right anterior section. However, using this technique remnant donor liver is often too small. Here, we introduce a technical Modified extended right hepatectomy (MERH), in which the MHV was excavated preserving the entire Sg4 in the donor.
We compared clinical outcomes between donors using our technique (n=12) that may result in Sg4 congestion, and right hepatectomy (RH, n=12) that may not. MERH was performed when the remnant donor liver had a volume exceeding 35% and showed no steatosis in preoperative imaging study.
No donor died, and there were no differences in operative time and postoperative recovery between the two groups (p>0.05). The regeneration of the remnant liver after MERH and RH were similar (160.2% vs. 187.7% at POD 10; 222.2% vs. 230.5% at 4 months) (p>0.05).
Our results show that MERH didn't impair recovery or liver regeneration in donors, and indicate that MERH will be useful in adult living donor liver transplantation.
背景/目的:为克服成人受体肝脏移植供肝不足的问题,同时解决右前叶淤血,需进行供体扩大右肝切除术,包括切除肝中静脉(MHV)和部分肝段4(Sg4)。然而,采用这种技术时,供体残余肝脏往往过小。在此,我们介绍一种改良扩大右肝切除术(MERH)技术,即保留供体的整个Sg4并切除MHV。
我们比较了采用可能导致Sg4淤血的技术的供体(n = 12)和可能不会导致Sg4淤血的右肝切除术(RH,n = 12)的临床结果。当供体残余肝脏体积超过35%且术前影像学检查未显示脂肪变性时,实施MERH。
无供体死亡,两组间手术时间和术后恢复情况无差异(p>0.05)。MERH和RH术后残余肝脏的再生情况相似(术后第10天分别为160.2%和187.7%;4个月时分别为222.2%和230.5%)(p>0.05)。
我们的结果表明,MERH不会损害供体的恢复或肝脏再生,提示MERH在成人活体肝移植中具有应用价值。