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《西北阿德莱德健康研究:特定慢性病队列的详细方法与基线分层》

The North West Adelaide Health Study: detailed methods and baseline segmentation of a cohort for selected chronic diseases.

作者信息

Grant Janet F, Chittleborough Catherine R, Taylor Anne W, Dal Grande Eleonora, Wilson David H, Phillips Patrick J, Adams Robert J, Cheek Julianne, Price Kay, Gill Tiffany, Ruffin Richard E

机构信息

Population Research & Outcome Studies Unit, South Australian Department of Health, 11 Hindmarsh Square, Adelaide, 5000, South Australia.

出版信息

Epidemiol Perspect Innov. 2006 Apr 12;3:4. doi: 10.1186/1742-5573-3-4.

Abstract

The North West Adelaide Health Study is a population-based biomedical cohort study investigating the prevalence of a number of chronic conditions and health-related risk factors along a continuum. This methodology may assist with evidence-based decisions for health policy makers and planners, and inform health professionals who are involved in chronic disease prevention and management, by providing a better description of people at risk of developing or already diagnosed with selected chronic conditions for more accurate targeting groups for health gain and improved health outcomes. Longitudinal data will provide information on progression of chronic conditions and allow description of those who move forward and back along the continuum over time. Detailed methods are provided regarding the random recruitment and examination of a representative sample of participants (n = 4060), including the rationale for various processes and valuable lessons learnt. Self-reported and biomedical data were obtained on risk factors (smoking, alcohol consumption, physical activity, family history, body mass index, blood pressure, cholesterol) and chronic conditions (asthma, chronic obstructive pulmonary disease, diabetes) to classify participants according to their status along a continuum. Segmenting this population sample along a continuum showed that 71.5% had at least one risk factor for developing asthma, chronic obstructive pulmonary disease or diabetes. Almost one-fifth (18.8%) had been previously diagnosed with at least one of these chronic conditions, and an additional 3.9% had at least one of these conditions but had not been diagnosed. This paper provides a novel opportunity to examine how a cohort study was born. It presents detailed methodology behind the selection, recruitment and examination of a cohort and how participants with selected chronic conditions can be segmented along a continuum that may assist with health promotion and health services planning.

摘要

西北阿德莱德健康研究是一项基于人群的生物医学队列研究,旨在调查一系列慢性病和健康相关风险因素在连续体上的患病率。这种方法可以通过更准确地确定健康改善和改善健康结果的目标群体,为卫生政策制定者和规划者提供基于证据的决策依据,并为参与慢性病预防和管理的卫生专业人员提供信息。纵向数据将提供有关慢性病进展的信息,并允许描述那些随着时间在连续体上向前和向后移动的人。文中提供了关于随机招募和检查代表性参与者样本(n = 4060)的详细方法,包括各种流程的原理和吸取的宝贵经验教训。通过自我报告和生物医学数据获取了风险因素(吸烟、饮酒、体育活动、家族病史、体重指数、血压、胆固醇)和慢性病(哮喘、慢性阻塞性肺疾病、糖尿病)的信息,以便根据参与者在连续体上的状态进行分类。将该人群样本沿连续体进行划分显示,71.5%的人至少有一个患哮喘、慢性阻塞性肺疾病或糖尿病的风险因素。近五分之一(18.8%)的人此前已被诊断患有一种或多种这些慢性病,另有3.9%的人患有这些疾病中的至少一种但未被诊断。本文提供了一个审视队列研究如何诞生的新机会。它介绍了队列选择、招募和检查背后的详细方法,以及如何将患有选定慢性病的参与者沿连续体进行划分,这可能有助于健康促进和卫生服务规划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/272d/1462963/098774d8f7f7/1742-5573-3-4-1.jpg

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