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妊娠期间与原发性甲状旁腺功能亢进相关的高钙血症危象

[Hypercalcemic crisis associated with primary hyperparathyroidism during pregnancy].

作者信息

Branco Miguel R, Rodrigues Carla T, Campos António, Figueiredo Ana, Coucelo João, Magalhães Carlos, Silva Isabel S, Taborda Adelaide, Almeida Maria Céu

机构信息

Unidade de Diagnóstico Pré-Natal/Medicina Fetal, Maternidade Bissaya Barreto, Centro Hospitalar de Coimbra, Coimbra.

出版信息

Acta Med Port. 2005 Sep-Oct;18(5):395-8. Epub 2005 Oct 16.

Abstract

Primary hyperparathyroidism is a rare occurrence in pregnancy with significant risks to the mother and the foetus, witch is related to the level of serum calcium. A 41-year-old women, gravida 2, para 1, presented at 22 weeks gestation with nausea, vomiting and mild cognitive dysfunction associated with hypercalcemic crisis. The hypercalcemia was observed to be related to parathyroid hyperplasia that was surgically removed. Complete resolution of her symptomatology and hypercalcemia occurred postoperatively. The pregnancy was complicated with transient hypertension. A small for gestational age healthy male infant was delivered at term with no neonatal complications related with this pathology.

摘要

原发性甲状旁腺功能亢进在妊娠期间很少见,对母亲和胎儿有重大风险,这与血清钙水平有关。一名41岁、孕2产1的妇女在妊娠22周时出现恶心、呕吐和与高钙血症危象相关的轻度认知功能障碍。观察到高钙血症与甲状旁腺增生有关,随后通过手术切除。术后她的症状和高钙血症完全缓解。妊娠合并短暂性高血压。足月分娩出一名小于胎龄的健康男婴,未出现与此病症相关的新生儿并发症。

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