Sankar Pamela, Wolpe Paul Root, Jones Nora L, Cho Mildred
Center for Bioethics, University of Pennsylvania, Philadelphia, PA 19104, USA.
Community Genet. 2006;9(2):78-86. doi: 10.1159/000091484.
To examine the role of the practitioner, informed consent, and genetic counseling in genetic testing decisions and to assess their relative influence on women's decision to have clinical BRCA1/2 testing.
Qualitative study using in-depth open-ended interviews with 68 women who had considered clinical BRCA1/2 testing.
Slightly less than half of the women who had considered BRCA1/2 testing were found to have had a clear and preexisting desire to test or not to test, irrespective of practitioner attitude or advice.
The decision to accept or decline genetic testing is the result of a complex process that goes beyond interactions between health care providers and patients, indicating a caution against exclusive reliance on informed consent or counseling encounters.
探讨从业者、知情同意和遗传咨询在基因检测决策中的作用，并评估它们对女性进行临床BRCA1/2检测决策的相对影响。
采用定性研究方法，对68名考虑进行临床BRCA1/2检测的女性进行深入的开放式访谈。
发现略少于一半考虑进行BRCA1/2检测的女性，无论从业者的态度或建议如何，都有明确且预先存在的检测或不检测的意愿。
接受或拒绝基因检测的决定是一个复杂过程的结果，该过程超越了医疗保健提供者与患者之间的互动，这表明应谨慎避免单纯依赖知情同意或咨询过程。
