• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项针对麻风病患者鼻旁窦内窥镜检查的十年历史研究。

A ten-year historic study of paranasal cavity endoscopy in patients with Leprosy.

作者信息

Martins Ana C C, Castro Jair de Carvalho e, Moreira João Soares

机构信息

Instituto de Pesquisa Clínica Evandro Chagas-Fiocruz.

出版信息

Braz J Otorhinolaryngol. 2005 Sep-Oct;71(5):609-15. doi: 10.1016/s1808-8694(15)31265-9. Epub 2006 Mar 31.

DOI:10.1016/s1808-8694(15)31265-9
PMID:16612522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9441970/
Abstract

UNLABELLED

Leprosy is an infectious condition that has a chronic evolution caused by the Mycobacterium leprae. It very often attacks the nasal cavities mucosa independent of its clinical form, even before skin lesions or lesions to other parts of the body arise, in the presence or not of clinical complaints.

AIM

To show the efficiency of nasal endoscopy to identify endonasal mucosa lesions and the importance of the Otorhinolaryngologist in the diagnosis and follow-up of Leprosy patients.

STUDY DESIGN

Clinical history study.

MATERIAL AND METHOD

A historic study was performed with 173 patient's records without previous treatment from 1990 to 2000 at the Otorhinolaryngology Services, Instituto de Pesquisas Clinicas Hospital Evandro Chagas, Fiocruz.

RESULTS

All of the patients showed nasal lesions, 121 with and 52 without clinical complaints.

DISCUSSION

Nasal cavities endoscopy exam enabled early identification of the mucosa alteration in Leprosy patients as well as how to identify the evolution of the lesions. This type of exam also helps to establish local treatment.

CONCLUSION

The evaluation and follow-up of Leprosy patients by the Otorhinolaryngologist in a multidisciplinary team are justified and offer the patient early diagnosis and specific treatment.

摘要

未标注

麻风病是一种由麻风分枝杆菌引起的具有慢性病程的传染病。无论其临床类型如何,它常常侵袭鼻腔黏膜,甚至在皮肤病变或身体其他部位出现病变之前,无论有无临床症状。

目的

展示鼻内镜检查在识别鼻内黏膜病变方面的有效性以及耳鼻喉科医生在麻风病患者诊断和随访中的重要性。

研究设计

临床病史研究。

材料与方法

对1990年至2000年期间在Evandro Chagas临床研究医院(Fiocruz)耳鼻喉科服务部门未经治疗的173例患者的病历进行了一项历史性研究。

结果

所有患者均有鼻腔病变,其中121例有临床症状,52例无临床症状。

讨论

鼻腔内镜检查能够早期识别麻风病患者的黏膜改变以及病变的发展情况。这种检查类型也有助于确定局部治疗方案。

结论

耳鼻喉科医生在多学科团队中对麻风病患者进行评估和随访是合理的,可为患者提供早期诊断和特异性治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/209b/9441970/e0a5b3225760/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/209b/9441970/ae44245c92f5/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/209b/9441970/479ae21dc9c6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/209b/9441970/869c1abd7915/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/209b/9441970/e0a5b3225760/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/209b/9441970/ae44245c92f5/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/209b/9441970/479ae21dc9c6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/209b/9441970/869c1abd7915/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/209b/9441970/e0a5b3225760/gr4.jpg

相似文献

1
A ten-year historic study of paranasal cavity endoscopy in patients with Leprosy.一项针对麻风病患者鼻旁窦内窥镜检查的十年历史研究。
Braz J Otorhinolaryngol. 2005 Sep-Oct;71(5):609-15. doi: 10.1016/s1808-8694(15)31265-9. Epub 2006 Mar 31.
2
The paranasal sinuses in lepromatous leprosy.
Lepr India. 1979 Oct;51(4):481-5.
3
Radiological changes in the paranasal sinuses in lepromatous leprosy.瘤型麻风患者鼻窦的放射学改变
J Laryngol Otol. 1979 Jun;93(6):597-600. doi: 10.1017/s0022215100087454.
4
Chronic lymphocytic leukemia manifesting in the paranasal sinuses.鼻窦表现的慢性淋巴细胞白血病。
Otolaryngol Head Neck Surg. 2002 Dec;127(6):582-4. doi: 10.1067/mhn.2002.129819.
5
Contribution of nasal biopsy to leprosy diagnosis.
Am J Rhinol Allergy. 2009 Mar-Apr;23(2):177-80. doi: 10.2500/ajra.2009.23.3301.
6
Preoperative evaluation of chronic rhinosinusitis patients by conventional radiographies, computed tomography and nasal endoscopy.通过传统放射学、计算机断层扫描和鼻内镜检查对慢性鼻窦炎患者进行术前评估。
Kulak Burun Bogaz Ihtis Derg. 2009 Jul-Aug;19(4):184-91.
7
Evolution of nasal mucosal lesions in leprosy (histological study).麻风病鼻黏膜病变的演变(组织学研究)
Lepr India. 1981 Jan;53(1):11-6.
8
Importance of nasal lesions in early lepromatous leprosy.鼻损害在早期瘤型麻风病中的重要性。
Ann R Coll Surg Engl. 1975 Dec;57(6):309-12.
9
Endoscopic endonasal sinus surgery. A long-term follow-up study.鼻内镜鼻窦手术。一项长期随访研究。
Acta Otolaryngol. 1996 Jul;116(4):611-9. doi: 10.3109/00016489609137898.
10
Paranasal sinus computed tomography findings in patients treated for lepromatous leprosy.瘤型麻风患者的鼻窦计算机断层扫描结果
J Laryngol Otol. 2007 Jan;121(1):15-8. doi: 10.1017/S0022215106002489. Epub 2006 Jul 31.

引用本文的文献

1
Leprosy in skeletons from archaeological sites: A systematic review.考古遗址骨骼中的麻风病:一项系统综述。
PLoS Negl Trop Dis. 2025 Aug 19;19(8):e0013374. doi: 10.1371/journal.pntd.0013374. eCollection 2025 Aug.
2
A Case of Saddle Nose Deformity Secondary to Lepromatous Leprosy.1例瘤型麻风继发鞍鼻畸形病例
Indian J Otolaryngol Head Neck Surg. 2025 Feb;77(2):1014-1018. doi: 10.1007/s12070-024-05238-x. Epub 2024 Nov 28.
3
Sporotrichosis in the nasal mucosa: A single-center retrospective study of 37 cases from 1998 to 2020.

本文引用的文献

1
Study of ethmoid sinus involvement in multibacillary leprosy.多菌型麻风病筛窦受累情况的研究。
J Laryngol Otol. 1998 Nov;112(11):1038-41. doi: 10.1017/s0022215100142410.
2
The nose in leprosy: immunohistology of the nasal mucosa.麻风病中的鼻子:鼻黏膜的免疫组织学
Int J Lepr Other Mycobact Dis. 1998 Sep;66(3):328-39.
3
Microscopic rhinoscopy in lepromatous leprosy.瘤型麻风的显微鼻镜检查
鼻腔孢子丝菌病:1998 年至 2020 年单中心回顾性研究 37 例。
PLoS Negl Trop Dis. 2023 Mar 27;17(3):e0011212. doi: 10.1371/journal.pntd.0011212. eCollection 2023 Mar.
J Laryngol Otol. 1997 Feb;111(2):122-4. doi: 10.1017/s0022215100136631.
4
The nose in lepromatous leprosy; bacteriological and histopathological studies of patients treated with dapsone monotherapy for varying periods of time.
Int J Lepr Other Mycobact Dis. 1982 Mar;50(1):58-67.
5
Quantitative estimation of Mycobacterium leprae in exhaled nasal breath.呼出鼻息中麻风分枝杆菌的定量估计。
Lepr Rev. 1983 Dec;54(4):337-40. doi: 10.5935/0305-7518.19830040.
6
The histopathological appearance of leprous rhinitis and pathogenesis of septal perforation in leprosy.麻风性鼻炎的组织病理学表现及麻风病鼻中隔穿孔的发病机制。
J Laryngol Otol. 1966 Jul;80(7):718-32. doi: 10.1017/s0022215100065890.
7
[Endonasal microsurgery].[鼻内镜显微手术]
Acta Otorinolaryngol Iber Am. 1970;21(2):184-92.
8
The nose in leprosy: steps to a better understanding.麻风病中的鼻子:增进理解的步骤
Lepr Rev. 1974 Jun;45(2):97-103. doi: 10.5935/0305-7518.19740011.
9
A clinical study of the nose in lepromatous leprosy.瘤型麻风病鼻部的临床研究。
Lepr Rev. 1974 Jun;45(2):135-44. doi: 10.5935/0305-7518.19740015.
10
The management of leprous rhinitis.麻风性鼻炎的治疗
Lepr Rev. 1973 Dec;44(4):186-91. doi: 10.5935/0305-7518.19730025.