Hsieh Ching-Hua, Huang Kuo-Feng, LiLiang Po-Chou, Jeng Seng-Feng, Tsai Hui-Hong
Dept. of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Clin Auton Res. 2006 Jun;16(3):223-7. doi: 10.1007/s10286-006-0340-9. Epub 2006 Apr 12.
When the fingers are immersed in water digital blood flow is reduced and the skin wrinkles, suggesting that vasoconstriction plays a role. However, is wrinkling due to sympathetic activation or some intrinsic property of the skin? To define the role of autonomic innervation in skin wrinkling we measured changes in blood perfusion (Laser Doppler Perfusion Imager) in 20 successfully replanted fingers (mean time after complete amputation 17.5 +/- 5.2 months). We compared responses in replanted fingers with those in corresponding contralateral normal fingers before and immediately after immersion in saline (0.5 mol/l NaCl at 40 degrees C). In the normal fingers, immersion caused a decrease in blood flow by 27.6 +/- 11.5% and skin wrinkling. However, in the replanted fingers blood flow increased by 22.8 +/- 19.6% and the skin did not wrinkle. The paradoxical cutaneous vasodilatation and absence of wrinkling in the denervated fingers suggests that sympathetic innervation is important in water-immersion skin wrinkling.
当手指浸入水中时，指部血流减少，皮肤起皱，这表明血管收缩起了作用。然而，皮肤起皱是由于交感神经激活还是皮肤的某些内在特性呢？为了确定自主神经支配在皮肤起皱中的作用，我们测量了20根成功再植手指（完全离断后平均时间为17.5±5.2个月）的血液灌注变化（激光多普勒灌注成像）。我们比较了再植手指与对侧相应正常手指在浸入盐水（40℃的0.5mol/L氯化钠）之前和之后即刻的反应。在正常手指中，浸入导致血流减少27.6±11.5%，皮肤起皱。然而，在再植手指中，血流增加了22.8±19.6%，皮肤没有起皱。去神经手指中出现的矛盾性皮肤血管扩张和不起皱表明，交感神经支配在浸水皮肤起皱中很重要。
