Imperiali G, Terpin M M, Meucci G, Ferrara A, Minoli G
Department of Gastroenterology, Ospedale Valduce, Como, Italy.
Endoscopy. 2006 Jun;38(6):610-2. doi: 10.1055/s-2006-924985. Epub 2006 Apr 12.
We performed a long-term follow-up study of patients with segmental colitis associated with diverticula, in order to clarify the natural history of this disease.
We identified 15 patients who were diagnosed as having segmental colitis associated with diverticula during 1997. We assessed these patients by means of periodic follow-up visits from 1997 to 2004.
Eight of the 15 patients had no clinical recurrence during follow-up. Five patients had sporadic recurrences that were clinically mild (on average, one in 5 years), which responded to topical therapy and often to self-medication. Only two patients were diagnosed during the follow-up period as having Crohn's disease; notably, these were the only patients who did not have hematochezia as the main symptom at onset.
The course of this disease appears to be substantially benign.
我们对憩室相关节段性结肠炎患者进行了长期随访研究,以阐明该疾病的自然病程。
我们确定了15例在1997年被诊断为憩室相关节段性结肠炎的患者。从1997年至2004年,我们通过定期随访对这些患者进行了评估。
15例患者中有8例在随访期间无临床复发。5例患者有散发性复发,临床症状较轻(平均每5年发作1次),对局部治疗有反应,且常可通过自我用药缓解。随访期间仅2例患者被诊断为克罗恩病;值得注意的是,这2例是仅有的起病时不以便血为主要症状的患者。
该疾病的病程似乎基本呈良性。