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[经心尖主动脉管道置入术治疗老年获得性主动脉瓣狭窄合并小主动脉瓣环患者]

[Apicoaortic conduit insertion for elderly patients with acquired aortic stenosis and small aortic annulus].

作者信息

Takemura T, Tsuda Y

机构信息

Department of Cardiovascular Surgery, National Health Organization Nagano Hospital, Ueda, Japan.

出版信息

Kyobu Geka. 2006 Apr;59(4):294-300.

Abstract

BACKGROUND

Patients with critical aortic stenosis, a heavily calcified aorta, and a small aortic annulus are at an increasing risk of complications during a conventional aortic valve replacement (AVR) procedure. Insertion of an apicoaortic conduit (AAC) can be an alternative to AVR in such situations. This study is a review of our experiences with AAC in elderly patients with acquired aortic stenosis.

METHOD

From 2001 to 2005, 7 elderly patients (mean age of 81 : range 74 to 87) underwent an AAC insertion for severe symptomatic aortic stenosis with a small aortic annulus (mean annulus size 17.9 mm). Preoperatively, all were symptomatic, with 4 rated as New York Heart Association (NYHA) functional class IV, 2 as class III, and 1 as class II. In addition, 3 patients had severe congestive heart failure with mechanical ventilation and received a high dose administration of catecholamine, and 1 had undergone coronary artery bypass grafting (CABG) previously.

RESULT

The AAC insertions were performed under a cardiopulmonary bypass through a left thoracotomy in 6 patients, while 1 patient underwent the procedure without a cardiopulmonary bypass. Distal anastomoses were performed in the descending thoracic aorta with a partial occluding clamp. A composite woven Dacron conduit with a stented biological valve was used in 2 cases, and a woven Dacron conduit with a stentless bioprosthesis was used in 5. Two patients underwent a concomitant CABG. There was 1 hospital death due to obstructive ileus 4 months after the operation. One patient who had been in a shock state preoperatively had hypoxic encephalopathy due to inoperative severe hypotension. Postoperative echocardiography showed relief of the left ventricle-aortic gradient in all patients. After a mean follow-up period of 22 months, there was no late death, while 3 patients were readmitted due to congestive heart failure. Further, 1 of the patients was rated as NYHA class I, 1 as class II, and 2 as class III.

CONCLUSION

An AAC procedure was found to be an acceptable alternative for elderly patients who had a high-risk of complications with the standard procedure.

摘要

背景

患有严重主动脉瓣狭窄、主动脉严重钙化且主动脉瓣环较小的患者,在传统主动脉瓣置换(AVR)手术期间发生并发症的风险日益增加。在这种情况下,插入心尖主动脉导管(AAC)可作为AVR的替代方案。本研究回顾了我们在老年获得性主动脉瓣狭窄患者中应用AAC的经验。

方法

2001年至2005年,7例老年患者(平均年龄81岁:范围74至87岁)因严重症状性主动脉瓣狭窄且主动脉瓣环较小(平均瓣环大小17.9mm)接受了AAC插入术。术前,所有患者均有症状,4例被评为纽约心脏协会(NYHA)功能IV级,2例为III级,1例为II级。此外,3例患者患有严重充血性心力衰竭并接受机械通气,且接受了高剂量儿茶酚胺治疗,1例患者先前接受过冠状动脉旁路移植术(CABG)。

结果

6例患者通过左胸切口在体外循环下进行AAC插入,1例患者未进行体外循环即接受了该手术。在降主动脉使用部分阻断钳进行远端吻合。2例使用带有带支架生物瓣膜的复合编织涤纶导管,5例使用带有无支架生物假体的编织涤纶导管。2例患者同时进行了CABG。术后4个月有1例患者因肠梗阻死亡。1例术前处于休克状态的患者因术中严重低血压出现缺氧性脑病。术后超声心动图显示所有患者左心室-主动脉压差均有所缓解。平均随访22个月后,无晚期死亡病例,3例患者因充血性心力衰竭再次入院。此外,1例患者被评为NYHA I级,1例为II级,2例为III级。

结论

对于标准手术并发症风险高的老年患者,AAC手术被认为是一种可接受的替代方案。

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