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Development of opioid peptide analogs as pharmacologic tools and as potential drugs: current status and future directions.

作者信息

Schiller P W

机构信息

Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal, Quebec, Canada.

出版信息

NIDA Res Monogr. 1991;112:180-97.

PMID:1661377
Abstract
摘要

相似文献

1
Development of opioid peptide analogs as pharmacologic tools and as potential drugs: current status and future directions.
NIDA Res Monogr. 1991;112:180-97.
2
The use of conformational restriction and molecular modeling techniques in the development of receptor-specific opioid peptide agonists and antagonists.
NIDA Res Monogr. 1993;134:238-52.
3
Conformational analysis of opioid receptor-selective peptides using nuclear magnetic resonance and theoretical calculations.利用核磁共振和理论计算对阿片受体选择性肽进行构象分析。
NIDA Res Monogr. 1991;112:198-217.
4
Opioid receptors: development of selective peptidomimetics with agonist or antagonist activity.阿片受体：具有激动剂或拮抗剂活性的选择性肽模拟物的开发。
Farmaco. 1991 Jan;46(1 Suppl):171-5.
5
Design of conformationally constrained cyclic peptides with high delta and mu opioid receptor specificities.具有高δ和μ阿片受体特异性的构象受限环肽的设计。
NIDA Res Monogr. 1986;69:128-47.
6
Synthetic peptide combinatorial libraries may be used to determine peptide ligands for opioid receptors.合成肽组合文库可用于确定阿片受体的肽配体。
NIDA Res Monogr. 1993;134:66-74.
7
[Electrophysiological aspects of the properties of potentially addictive drugs].
Acta Psychiatr Belg. 1990 Jan-Feb;90(1):37-45.
8
Mechanistic structure-activity studies of peptide and nonpeptide flexible opioids: an interdisciplinary approach.肽类和非肽类柔性阿片样物质的结构-活性机制研究：一种跨学科方法。
NIDA Res Monogr. 1986;69:231-65.
9
In vitro and in vivo characterization of opioid activities of endomorphins analogs with novel constrained C-terminus: evidence for the important role of proper spatial disposition of the third aromatic ring.
Peptides. 2007 Apr;28(4):859-70. doi: 10.1016/j.peptides.2007.01.002. Epub 2007 Jan 13.
10
Molecular biology of opioid receptors.阿片受体的分子生物学
NIDA Res Monogr. 1996;161:83-103.

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The cis-4-amino-L-proline residue as a scaffold for the synthesis of cyclic and linear endomorphin-2 analogues.顺式-4-氨基-L-脯氨酸残基作为合成环型和线型内吗啡肽-2 类似物的支架。
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