Manderbacka Kristiina, Hetemaa Tiina, Keskimäki Ilmo, Luukkainen Pekka, Koskinen Seppo, Reunanen Antti
Outcomes and Equity Research Group, National Research and Development Centre for Welfare and Health (STAKES), PO Box 220, 00531 Helsinki, Finland.
J Epidemiol Community Health. 2006 May;60(5):442-7. doi: 10.1136/jech.2005.041566.
Systematic socioeconomic differences in mortality have been reported among myocardial infarction (MI) patients in many countries, including Finland. The findings have been similar irrespective of country, study period, age group, or length of follow up, but few studies have examined the disparities among other groups of coronary patients. This study examined whether similar socioeconomic differences in outcomes exist among patients with angina pectoris (AP).
The data were based on individual register linkages among a population based 40-79 year-old cohort of 61,350 patients with incident AP or MI during 1995-1998 in Finland. Two year coronary heart disease mortality and one year MI incidence and its 28 day case fatality was studied among AP patients using Cox's and logistic regression analysis, and the results compared with those of the MI patient group.
A clear socioeconomic pattern was found in two year coronary heart disease (CHD) mortality: the lower the socioeconomic group the higher the mortality risk. The socioeconomic patterning of mortality was similar to that found among MI patients. Controlling for comorbidity or disease severity did not change the results. Among AP patients a similar pattern was also found in MI incidence during the follow up, but no systematic socioeconomic differences were detected in its 28 day case fatality.
Socioeconomic differences in CHD outcomes also exist among angina patients. These results suggest that targeted measures of secondary prevention are needed among CHD patients with lower socioeconomic status to reduce socioeconomic disparities in fatal and non-fatal coronary events.
在包括芬兰在内的许多国家,心肌梗死(MI)患者中已报告存在系统性的社会经济死亡率差异。无论国家、研究时期、年龄组或随访时间长短,研究结果都相似,但很少有研究考察其他冠心病患者群体之间的差异。本研究调查了心绞痛(AP)患者中是否存在类似的社会经济结局差异。
数据基于芬兰1995 - 1998年期间以人群为基础的40 - 79岁队列中61350例新发AP或MI患者的个体登记关联。使用Cox回归和逻辑回归分析研究AP患者的两年冠心病死亡率、一年MI发病率及其28天病死率,并将结果与MI患者组进行比较。
在两年冠心病(CHD)死亡率中发现了明显的社会经济模式:社会经济群体越低,死亡风险越高。死亡率的社会经济模式与MI患者中发现的相似。控制合并症或疾病严重程度并未改变结果。在AP患者中,随访期间MI发病率也发现了类似模式,但在其28天病死率中未检测到系统性的社会经济差异。
心绞痛患者中也存在冠心病结局的社会经济差异。这些结果表明,需要对社会经济地位较低的冠心病患者采取有针对性的二级预防措施,以减少致命和非致命性冠心病事件中的社会经济差异。