Kim Ickkeun, Lee Jue Yong, Kwon Jung Hye, Jung Joo Young, Song Hun Ho, Park Young Iee, Ro Eusun, Choi Kyung Chan
Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, Korea.
J Korean Med Sci. 2006 Apr;21(2):365-7. doi: 10.3346/jkms.2006.21.2.365.
Autoimmune hemolytic anemia associated with an ovarian teratoma is a very rare disease. However, treating teratoma is the only method to cure the hemolytic anemia, so it is necessary to include ovarian teratoma in the differential diagnosis of autoimmune hemolytic anemia. We report herein on a case of a young adult patient who had severe autoimmune hemolytic anemia that was induced by an ovarian teratoma. A 25-yr-old woman complained of general weakness and dizziness for 1 week. The hemoglobin level was 4.2 g/dL, and the direct and indirect antiglobulin tests were all positive. The abdominal computed tomography scan revealed a huge left ovarian mass, and this indicated a teratoma. She was refractory to corticosteroid therapy; however, after surgical resection of the ovarian mass, the hemoglobin level and the reticulocyte count were gradually normalized. The mass was well encapsulated and contained hair and teeth. She was diagnosed as having autoimmune hemolytic anemia associated with an ovarian teratoma. To the best of our knowledge, this is the first such a case to be reported in Korea.
与卵巢畸胎瘤相关的自身免疫性溶血性贫血是一种非常罕见的疾病。然而，治疗畸胎瘤是治愈溶血性贫血的唯一方法，因此有必要将卵巢畸胎瘤纳入自身免疫性溶血性贫血的鉴别诊断中。我们在此报告一例年轻成年患者，其严重的自身免疫性溶血性贫血由卵巢畸胎瘤诱发。一名25岁女性主诉全身乏力和头晕1周。血红蛋白水平为4.2 g/dL，直接和间接抗球蛋白试验均为阳性。腹部计算机断层扫描显示左卵巢有一个巨大肿块，提示为畸胎瘤。她对皮质类固醇治疗无效；然而，在手术切除卵巢肿块后，血红蛋白水平和网织红细胞计数逐渐恢复正常。肿块包膜完整，含有毛发和牙齿。她被诊断为与卵巢畸胎瘤相关的自身免疫性溶血性贫血。据我们所知，这是韩国首例此类病例报告。
