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妊娠期特发性颅内高压的治疗选择及分娩方式

Choice of therapy and mode of delivery in idiopathic intracranial hypertension during pregnancy.

作者信息

Bagga Rashmi, Jain Vanita, Das Chandi Prasad, Gupta Kamla Rani, Gopalan Sarala, Malhotra Sarla

机构信息

Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education & Research, Sector-12, Chandigarh, India.

出版信息

MedGenMed. 2005 Nov 10;7(4):42.

Abstract

Benign intracranial hypertension (BIH) or idiopathic intracranial hypertension (IIH) is a rare disorder of unknown etiology that is most often seen in obese women of reproductive age (19.3/100,000) and is reported only occasionally during pregnancy. Both pregnancy and exogenous estrogens are thought to promote IIH or worsen it. It can occur in any trimester during pregnancy, and the visual outcome is the same as for nonpregnant patients with IIH. There is no increase in fetal wastage; therapeutic abortion to limit its progression is not indicated, and subsequent pregnancies do not increase the risk of recurrence. Most therapies used during the nonpregnant state can also be used during pregnancy. The aim of treatment is to preserve vision and improve symptoms. Treatments include analgesics, diuretics, steroids, and serial lumbar punctures. When medical therapy fails, surgical procedures need to be considered. Although this condition has been reviewed often, the issue of mode of delivery, especially when papilledema has not resolved, is unclear. We report on 3 women with IIH during pregnancy and review the choice of therapy and mode of delivery.

摘要

良性颅内高压(BIH)或特发性颅内高压(IIH)是一种病因不明的罕见疾病,多见于育龄肥胖女性(发病率为19.3/10万),孕期仅偶尔有报道。妊娠和外源性雌激素均被认为会促使IIH发生或使其加重。它可发生于孕期的任何阶段,视力预后与非妊娠IIH患者相同。胎儿流产率并无增加;不建议进行治疗性流产以限制其进展,后续妊娠也不会增加复发风险。非妊娠状态下使用的大多数治疗方法在孕期也可使用。治疗目的是保护视力并改善症状。治疗方法包括使用镇痛药、利尿剂、类固醇以及连续腰椎穿刺。当药物治疗无效时,需要考虑手术治疗。尽管对此病症已有诸多综述,但分娩方式的问题,尤其是视乳头水肿未消退时的分娩方式尚不清楚。我们报告3例孕期IIH患者,并对治疗选择和分娩方式进行综述。

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