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自闭症与发育迟缓:一项使用IBSE量表对幼儿进行的比较临床研究。

Autism and developmental delay: a comparative clinical study in very young children using IBSE scale.

作者信息

Desombre Hugues, Malvy Joelle, Roux Sylvie, de Villard Régis, Sauvage Dominique, Dalery Jean, Lenoir Pascal

机构信息

Unité de Psychopathologie de l'Enfant et de l'Adolescent Dépt. de Pédiatrie, Hôpital Edouard Herriot, Place d'Arsonval, 69437, Lyon Cedex 03, France.

出版信息

Eur Child Adolesc Psychiatry. 2006 Sep;15(6):343-51. doi: 10.1007/s00787-006-0540-9. Epub 2006 Apr 13.

DOI:10.1007/s00787-006-0540-9
PMID:16614787
Abstract

OBJECTIVE

This study improves the knowledge of early autistic symptomatology and research concerning (i) the significant differences in the behaviors of children with autistic disorder (AD) and children with a developmental delay (DD), and (ii) the influence of the cognitive delay on symptomatology.

METHOD

Two groups of 20 young children (7-42 months) were compared: children with AD, and those with DD. The groups were paired by chronological and developmental age. The comparison was extended to four subgroups composed according to age (younger and older children--<24 months, >24 months) and to the global development quotient (GDQ) (the more and less delayed). Each child was evaluated with the Infant Behavior Summarized Evaluation scale (IBSE).

RESULTS

For the younger AD children, significant differences affected social communication and their adaptation to the environment (intolerance to frustration, resistance to change). For the older children (>24 months), this study showed the rapid progression of the number of distinctive signs between AD and DD children according to age and/or developmental level.

CONCLUSIONS

Cognitive delay has an important influence on the symptomatology at the moment of initial recognition of an autistic syndrome. This study is a complement for the fuller understanding of the nature and early diagnosis of disorders specific to autism at the earliest phases of development.

摘要

目的

本研究增进了对早期自闭症症状学的认识,并涉及以下两方面的研究:(i)自闭症谱系障碍(AD)儿童与发育迟缓(DD)儿童行为上的显著差异;(ii)认知延迟对症状学的影响。

方法

比较两组各20名幼儿(7 - 42个月):AD儿童和DD儿童。两组按实际年龄和发育年龄进行配对。比较扩展至根据年龄(年龄较小和较大儿童 - <24个月,>24个月)和整体发育商数(GDQ)(延迟较多和较少)组成的四个亚组。每个儿童均采用婴儿行为综合评估量表(IBSE)进行评估。

结果

对于年龄较小的AD儿童,显著差异影响社交沟通及其对环境的适应(不耐挫折、抗拒改变)。对于年龄较大的儿童(>24个月),本研究表明,根据年龄和/或发育水平,AD儿童与DD儿童之间独特症状数量的差异迅速增大。

结论

在首次识别自闭症综合征时,认知延迟对症状学有重要影响。本研究为更全面地理解自闭症特定障碍在发育最早阶段的性质和早期诊断提供了补充。

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