Brin I L, Kireeva T B
Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(8):9-11.
A study was made of pathological tonic reflexes (PTR) in adolescents afflicted with infantile cerebral paralysis (ICP) by means of assaying the tone of thigh muscles before and after treatment and in the presence of L-DOPA (nacom, 62.5 mg/day) intake. The drug minimized the manifestations of PTR because of changes in the function of brain structures involved in tonic reactions. It is recommended that during establishment of indications for +orthopedic-surgical treatment of ICP patients with marked PTR determining the formation of reflex contractures and deformities of limb joints, conservative treatment with L-DOPA drugs be preliminarily carried out.
通过测定治疗前后以及摄入左旋多巴(那可酮,62.5毫克/天)时大腿肌肉的张力,对患有婴儿脑性瘫痪(ICP)的青少年的病理性强直反射(PTR)进行了一项研究。由于参与强直反应的脑结构功能发生变化,该药物使PTR的表现最小化。建议在为有明显PTR的ICP患者确定反射性挛缩和肢体关节畸形形成的骨科手术治疗指征时,先进行左旋多巴药物的保守治疗。