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热带特发性下肢坏疽的诊断与临床表现综述。

A review of diagnosis and modes of presentation of tropical idiopathic lower limb gangrene.

作者信息

Musa A A

机构信息

Department of Surgery, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.

出版信息

Afr Health Sci. 2006 Mar;6(1):49-50. doi: 10.5555/afhs.2006.6.1.49.

DOI:10.5555/afhs.2006.6.1.49
PMID:16615828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1831962/
Abstract

BACKGROUND

Tropical idiopathic lower limb gangrene (TILLG) is also known as Symmetrical gangrene in the African, Idiopathic gangrene in the African and Idiopathic peripheral gangrene of the tropics. The aetiopathogenesis of this clinical entity is a mystery.

OBJECTIVE

To review methods of diagnosing tropical idiopathic lower limb gangrene (TILLG) and highlight its clinical variants.

METHOD

All Literature on idiopathic gangrene of the extremities was searched from libraries, colleagues and internet but only literature on TILLG (in Africans) from 1947 to date was scrutinised. Each case was studied to find out the basis of diagnosis.

RESULT

TILLG is not fully understood and not easy to recognise. Two sets of criteria are known to be helpful in establishing diagnosis. These criteria can be classified as major and minor criteria. Major criteria are those clinical data that can establish the diagnosis of TILLG. No devices are required to identify them. Minor criteria are pathological changes that are consistent with TILLG. Devices are required to identify them. Three pathomorphological types of TILLG were described in literature and are classified as types A, B and C.

CONCLUSIONS

This review is supposed to sensitise the clinician and make diagnosis easier. This will also encourage more researches. As more information becomes available, aetiopathogenesis of TILLG will be clearer and more clinical variants of the disease may be reported. This additional information will help in the prevention of gangrene, reducing the socioeconomic problems arising from amputation.

摘要

背景

热带特发性下肢坏疽(TILLG)在非洲也被称为对称性坏疽、非洲特发性坏疽和热带特发性周围坏疽。这种临床病症的病因发病机制仍是个谜。

目的

回顾热带特发性下肢坏疽(TILLG)的诊断方法,并突出其临床变体。

方法

从图书馆、同事及互联网搜索所有关于肢体特发性坏疽的文献,但仅仔细研究了1947年至今有关(非洲人)TILLG的文献。对每个病例进行研究以找出诊断依据。

结果

TILLG尚未被完全理解且不易识别。已知有两套标准有助于确立诊断。这些标准可分为主要标准和次要标准。主要标准是那些能够确立TILLG诊断的临床数据。无需借助设备即可识别。次要标准是与TILLG相符的病理变化。需要借助设备来识别。文献中描述了TILLG的三种病理形态类型,分别归类为A、B和C型。

结论

本综述旨在提高临床医生的认识并使诊断更容易。这也将鼓励更多研究。随着更多信息的获取,TILLG的病因发病机制将更加清晰,可能会报告该疾病更多的临床变体。这些额外信息将有助于预防坏疽,减少截肢带来的社会经济问题。

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本文引用的文献

1
Symmetrical gangrene in the African.非洲人的对称性坏疽
Br Med J. 1947 Jun 14;1(4510):847-9. doi: 10.1136/bmj.1.4510.847.
2
Tropical idiopathic lower limb gangrene: case report.热带特发性下肢坏疽:病例报告
East Afr Med J. 2001 Aug;78(8):447-8. doi: 10.4314/eamj.v78i8.9001.
3
A mode of presentation of tropical idiopathic lower limb gangrene in a neonate.新生儿热带特发性下肢坏疽的一种表现形式。
Trop Doct. 2001 Oct;31(4):226. doi: 10.1177/004947550103100420.
4
Idiopathic gangrene in African children.非洲儿童特发性坏疽
Br Med J. 1967 Sep 9;3(5566):646-8. doi: 10.1136/bmj.3.5566.646.
5
Peripheral gangrene in infancy and childhood.婴幼儿及儿童期的外周坏疽
Br Med J. 1967 Feb 25;1(5538):468-70. doi: 10.1136/bmj.1.5538.468.
6
"Idiopathic gangrene".特发性坏疽
East Afr Med J. 1970 Oct;47(10):506-14.
7
Idiopathic gangrene in African adults.非洲成年人特发性坏疽
Br Med J. 1972 Nov 4;4(5835):273-4. doi: 10.1136/bmj.4.5835.273.
8
Vascular changes in the idiopathic peripheral gangrene of the tropics.热带地区特发性周围坏疽的血管变化
Trop Geogr Med. 1972 Sep;24(3):219-25.
9
Necrotizing fasciitis of the extremities.肢体坏死性筋膜炎
J Trauma. 1992 Feb;32(2):179-82. doi: 10.1097/00005373-199202000-00011.