Hastings Michael H, Ebling Francis J P
MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, United Kingdom.
Cell. 2006 Apr 7;125(1):21-3. doi: 10.1016/j.cell.2006.03.019.
Hibernation is an extreme response to a seasonal environment, yet we know almost nothing about how it is timed or how vital cellular functions are sustained in the face of plummeting body temperature. In this issue of Cell, kondo et al. (2006) identify a liver-derived protein complex as an essential coordinator of this adaptation to the depredations of winter.
冬眠是对季节性环境的一种极端反应,但我们几乎对其时间安排方式以及在体温骤降的情况下细胞的重要功能是如何维持的一无所知。在本期《细胞》杂志中,近藤等人(2006年)确定了一种肝脏衍生的蛋白质复合物是这种适应冬季严酷环境的重要协调者。