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猫口腔肥大细胞瘤的诊断与治疗

Diagnosis and treatment of a feline oral mast cell tumor.

作者信息

Wright Zachary M, Chretin John D

机构信息

Small Animal Clinic, Texas A&M College of Veterinary Medicine, 4474 TAMU, College Station, TX, USA.

出版信息

J Feline Med Surg. 2006 Aug;8(4):285-9. doi: 10.1016/j.jfms.2006.01.007. Epub 2006 Apr 17.

DOI:10.1016/j.jfms.2006.01.007
PMID:16616568
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10822546/
Abstract

A cat was diagnosed with an oral mast cell tumor following incisional biopsy. The location of the tumor, possible metastasis, financial restraint and patient disposition severely limited therapeutic options. The patient was treated with six doses of 1-(2-chloroethyl)3-cyclohexyl-1-nitrosurea (CCNU) and methylprednisolone acetate. Complete remission was obtained after the third dosing regimen. This is the first documented case of feline oral mast cell tumor and one of a small group of cats with various cancers to be responsive to CCNU treatment.

摘要

一只猫在切开活检后被诊断为口腔肥大细胞瘤。肿瘤的位置、可能的转移、经济限制和患者的状况严重限制了治疗选择。该患者接受了六剂1-(2-氯乙基)-3-环己基-1-亚硝基脲（CCNU）和醋酸甲泼尼龙的治疗。在第三个给药方案后获得了完全缓解。这是第一例有记录的猫口腔肥大细胞瘤病例，也是一小群对CCNU治疗有反应的患有各种癌症的猫之一。

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本文引用的文献

1
Histopathology and biologic behavior of pleomorphic cutaneous mast cell tumors in fifteen cats.15只猫的多形性皮肤肥大细胞瘤的组织病理学与生物学行为
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J Vet Intern Med. 2001 May-Jun;15(3):196-9. doi: 10.1892/0891-6640(2001)015<0196:pieocl>2.3.co;2.
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Treatment of canine mast cell tumors with CCNU (lomustine).用环己亚硝脲（洛莫司汀）治疗犬肥大细胞瘤。
J Vet Intern Med. 1999 Nov-Dec;13(6):601-5. doi: 10.1892/0891-6640(1999)013<0601:tocmct>2.3.co;2.
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Pathol Vet. 1970;7(6):517-30. doi: 10.1177/030098587000700607.

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