Singh Mohan B, Bhalla Prem L
Plant Molecular Biology and Biotechnology Laboratory, ARC Centre of Excellence for Integrative Legume Research, Faculty of Land and Food Resources, The University of Melbourne, Parkville, Victoria 3010, Australia.
Trends Plant Sci. 2006 May;11(5):241-6. doi: 10.1016/j.tplants.2006.03.004. Epub 2006 Apr 17.
Stem cells are the precursors of differentiated cells and are, thus, indispensable for growth and development in plants and animals. Stem cells from both types of organisms share the fundamental features of a capacity for self-renewal and an ability to generate differentiated cells. The maintenance of stem cells in both systems is dependent upon reciprocal signalling between stem cells and the specialized tissue microenvironment known as the niche, which provides intercellular signals for stem cell regulation. One significantly underexplored facet of plant stem cells is the nature of their intrinsic transcriptional programme. A potentially rich avenue for addressing this deficiency is to combine laser-assisted microdissection and genome-wide transcriptional profiling to unravel the molecular road map controlling plant stem cells and their niches.
干细胞是分化细胞的前体，因此对于动植物的生长和发育不可或缺。来自这两类生物体的干细胞都具有自我更新能力和产生分化细胞的能力这两个基本特征。这两个系统中干细胞的维持都依赖于干细胞与被称为生态位的特殊组织微环境之间的相互信号传递，生态位为干细胞调控提供细胞间信号。植物干细胞一个显著未被充分探索的方面是其内在转录程序的性质。解决这一不足的一个潜在丰富途径是将激光辅助显微切割与全基因组转录谱分析相结合，以揭示控制植物干细胞及其生态位的分子路线图。
