Burgoyne Laura L, Anghelescu Doralina L, Tamburro Robert F, De Armendi Alberto J
Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN 38105-2794, USA.
Paediatr Anaesth. 2006 Apr;16(4):487-91. doi: 10.1111/j.1460-9592.2005.01765.x.
When anesthetizing a patient with an anterior mediastinal mass, sudden hypoxaemia and cardiovascular collapse may result from compression of a large airway or vascular structure in the mediastinum. We report the case of a pediatric cancer patient with an anterior mediastinal mass, who developed sudden and fatal hypoxaemia and cardiovascular collapse in the hours following sedation. A massive pulmonary thromboembolism was diagnosed at autopsy. We suggest that pulmonary embolism should be considered in the differential diagnosis when a patient with a mediastinal mass develops perioperative hypoxaemia, cardiovascular collapse, or both.
在对患有前纵隔肿块的患者进行麻醉时，纵隔内大气道或血管结构受压可能导致突然的低氧血症和心血管衰竭。我们报告了一例患有前纵隔肿块的儿科癌症患者，该患者在镇静后数小时内出现了突然且致命的低氧血症和心血管衰竭。尸检诊断为大面积肺血栓栓塞。我们建议，当纵隔肿块患者出现围手术期低氧血症、心血管衰竭或两者兼有时，在鉴别诊断中应考虑肺栓塞。
