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转移性肝细胞癌所致血胸伴大量咯血。

Hemothorax due to metastatic hepatocellular carcinoma presenting with massive hemoptysis.

作者信息

Wei Yu-Feng, Wang Hao-Chien, Chang Yi-Chen

机构信息

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

出版信息

J Formos Med Assoc. 2006 Apr;105(4):346-8. doi: 10.1016/S0929-6646(09)60127-3.

DOI:10.1016/S0929-6646(09)60127-3
PMID:16618616
Abstract

Hemoperitoneum caused by ruptured hepatocellular carcinoma (HCC) is not uncommon in patients with HCC. Hemothorax due to rupture of metastatic HCC, however, is a very rare complication with high mortality because of uncontrollable hemorrhage. We describe a 42-year-old male HCC patient with chest wall metastasis complicated by hemothorax with an unusual presentation of massive hemoptysis. He received tube thoracotomy immediately and emergency surgery because of persistent bleeding. Hemostasis was achieved transiently. Despite intensive care, he died of multiple organ failure on the 6th postoperative day. We conclude that hemothorax due to a ruptured HCC, as in this case, indicates a very poor prognosis despite intensive treatment.

摘要

肝细胞癌(HCC)破裂引起的腹腔积血在HCC患者中并不少见。然而,转移性HCC破裂导致的血胸是一种非常罕见的并发症,由于出血难以控制,死亡率很高。我们描述了一名42岁的男性HCC患者,其胸壁转移并发血胸,并伴有大量咯血这一不寻常表现。由于持续出血,他立即接受了开胸手术和急诊手术。出血暂时得到控制。尽管进行了重症监护,他还是在术后第6天死于多器官功能衰竭。我们得出结论,如本例所示,HCC破裂导致的血胸,尽管经过积极治疗,预后仍然很差。

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引用本文的文献

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Successful Transcatheter Arterial Embolization for Hemothorax from a Spontaneous Rupture of Hepatocellular Carcinoma Metastasis to the Chest Wall in an Elderly Patient.老年患者肝癌转移灶自发性破裂致血胸的成功经导管动脉栓塞治疗。
Intern Med. 2021 Jul 15;60(14):2223-2228. doi: 10.2169/internalmedicine.6003-20. Epub 2021 Feb 22.
2
Hepatocellular carcinoma with thoracic metastases presenting as hemothorax: A case report and literature review.以血胸为表现的伴有胸部转移的肝细胞癌:一例报告及文献复习
Medicine (Baltimore). 2018 Jun;97(22):e10945. doi: 10.1097/MD.0000000000010945.
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Transcatheter arterial embolization for chest wall metastasis of hepatocellular carcinoma.
经导管动脉栓塞术治疗肝细胞癌胸壁转移
World J Radiol. 2013 Feb 28;5(2):45-8. doi: 10.4329/wjr.v5.i2.45.
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Hemothorax caused by spontaneous rupture of hepatocellular carcinoma: a case report and review of the literature.自发性肝癌破裂导致血胸:病例报告及文献复习。
World J Surg Oncol. 2012 Oct 10;10:215. doi: 10.1186/1477-7819-10-215.
5
Hepatocellular carcinoma associated with hemorrhaging from iatrogenic rupture of a rib metastasis.
Gen Thorac Cardiovasc Surg. 2009 Jan;57(1):49-52. doi: 10.1007/s11748-008-0320-1. Epub 2009 Jan 22.