Bozza F, Marcelli V A, Pistilli R, Govoni F A, Marsico C
Department of Maxillofacial Surgery, ''San Filippo Neri'' Hospital, Rome, Italy.
Minerva Stomatol. 2006 Apr;55(4):215-22.
Maxillary ameloblastoma is a rare odontogenic neoplasm that is histologically benign and originates from epithelial cells present in bone tissue. If excised through conservative surgery, this tumour has a high relapse rate and is locally aggressive. The risk, in particularly extensive forms, that the ameloblastoma will invade extra-maxillary structures such as the orbit, the pterygomaxillary fossa, the infratemporal fossa and the base of the skull, means that surgical treatment is difficult if it is to be oncologically radical while respecting function and aesthetics. Thus, in these cases a complete and in-depth diagnostic work-up and careful planning of surgical treatment are needed: surgery entails an ablative phase with en-bloc resection of the neoformation to margins free of neoplastic infiltration, and a reconstruction phase that, within a short time-frame, will re-establish functionality and provide a good aesthetic result. Our experience in treating 2 cases of maxillary ameloblastoma is reported.
上颌成釉细胞瘤是一种罕见的牙源性肿瘤，组织学上为良性，起源于骨组织中的上皮细胞。如果通过保守手术切除，这种肿瘤复发率高且具有局部侵袭性。尤其是在肿瘤范围广泛的情况下，成釉细胞瘤有侵犯上颌外结构（如眼眶、翼上颌窝、颞下窝和颅底）的风险，这意味着如果要在保证功能和美观的同时进行根治性肿瘤手术，难度很大。因此，在这些病例中，需要进行全面深入的诊断检查并精心规划手术治疗：手术包括切除阶段，即整块切除肿瘤至切缘无肿瘤浸润，以及重建阶段，即在短时间内恢复功能并取得良好的美学效果。本文报道了我们治疗2例上颌成釉细胞瘤的经验。
