Uglov F G, Krutikova I F, Podozerskaia E N, Burmistrova M M, Rassadina S V
Vestn Khir Im I I Grek. 1991 Apr;146(4):3-7.
An experience with the treatment of 380 patients with rheumatic heart disease has shown that late stages of the disease are necessarily accompanied by the thromboembolic syndrome having exact clinical manifestations and definite stages. Pathogenesis of the thromboembolic syndrome is based on changes of the vascular bed, microcirculation and hemocoagulation parameters. So, control of factors of thrombus formation, prophylactics and therapy of thromboses and embolism are necessary in the process of surgical treatment of acquired heart diseases.
对380例风湿性心脏病患者的治疗经验表明，该疾病的晚期必然伴有具有确切临床表现和明确阶段的血栓栓塞综合征。血栓栓塞综合征的发病机制基于血管床、微循环和血液凝固参数的变化。因此，在后天性心脏病的外科治疗过程中，控制血栓形成因素、预防和治疗血栓及栓塞是必要的。
