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在委内瑞拉加拉加斯,面粉强化铁对降低学童贫血和缺铁患病率的影响:一项随访研究

Impact of fortification of flours with iron to reduce the prevalence of anemia and iron deficiency among schoolchildren in Caracas, Venezuela: a follow-up.

作者信息

Layrisse Miguel, García-Casal María Nieves, Méndez-Castellano Hernán, Jiménez Maritza, Henry Olavarría, Chávez José E, González Eglis

机构信息

Centro de Medicina Experimental, Laboratorio de Fisiopatología, Instituto Venezolano de Investigaciones Cientificas (IVIC), in Caracas, Venezuela.

出版信息

Food Nutr Bull. 2002 Dec;23(4):384-9. doi: 10.1177/156482650202300412.

Abstract

In Venezuela, a severe economic crisis starting in 1983 provoked a progressive reduction in the quantity and quality of food consumed by people from the low socioeconomic strata of the population. This situation resulted in a continuous increase in the prevalence of iron deficiency in the 1980s and 1990s. In 1993, an iron-fortification program was started, in which precooked corn and white wheat flours were enriched with iron, vitamin A, thiamine, niacin, and riboflavin. White wheat flour was enriched with the same nutrients, except for vitamin A. In 1996 we published the results of the impact of fortification of precooked corn and white wheat flours on the prevalence of anemia and iron deficiency in the population. A survey carried out in Caracas in 307 children aged 7, 11, and 15 years showed that the prevalence of iron deficiency measured by serum ferritin concentration dropped from 37% in 1992 to 16% in 1994, only one year after the iron-fortification program began. The prevalence of anemia, as measured by the hemoglobin concentration, diminished from 19% to 10% during the same period. This article reports the results of three other surveys carried out in 1997, 1998, and 1999 on children of the same age and socioeconomic groups that were evaluated in 1990, 1992, and 1994. There were no significant differences in anemia or iron deficiency among the last three surveys. The prevalence results from the last seven years seem to indicate that, after a dramatic reduction in 1994, iron deficiency tended to stabilize, while the prevalence of anemia increased to the same level found in 1992, before the fortification program started.

摘要

在委内瑞拉,始于1983年的严重经济危机导致社会经济地位较低阶层人群所消费食物的数量和质量逐渐下降。这种情况致使20世纪80年代和90年代缺铁患病率持续上升。1993年启动了一项铁强化计划,对预煮玉米粉和白小麦粉添加铁、维生素A、硫胺素、烟酸和核黄素进行强化。白小麦粉除不添加维生素A外,添加相同的营养素。1996年,我们发表了预煮玉米粉和白小麦粉强化对人群贫血和缺铁患病率影响的结果。1994年在加拉加斯对307名7岁、11岁和15岁儿童进行的一项调查显示,铁强化计划开始仅一年后,通过血清铁蛋白浓度测定的缺铁患病率从1992年的37%降至1994年的16%。同期,通过血红蛋白浓度测定的贫血患病率从19%降至10%。本文报告了1997年、1998年和1999年对1990年、1992年和1994年评估的相同年龄和社会经济群体儿童进行的另外三项调查结果。后三项调查中贫血或缺铁情况无显著差异。过去七年的患病率结果似乎表明,1994年大幅下降后,缺铁情况趋于稳定,而贫血患病率上升至强化计划开始前1992年的水平。

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