Halász P
Neurological Department, Postgraduate Medical School, Budapest, Hungary.
Epilepsy Res Suppl. 1991;2:43-8.
Polygraphic sleep investigations have shown that, in patients with generalized epilepsy and spike wave patterns, ictal electroclinical manifestations occur in intermediate periods between waking state-NREM sleep and NREM sleep-REM sleep. These physiological microfluctuations represent an important dynamic principle. These minor fluctuations are detectable with a special method of microanalysis of sleep. Such a microanalysis shows that the attacks of patients with generalized spike wave patterns are linked with arousal reactions. This may result in prolonged intermediate states causing augmentation of the paroxysms and thus representing a vicious circle.
多导睡眠监测表明，在全身性癫痫和棘波模式的患者中，发作期的电临床表现在清醒状态-非快速眼动睡眠和非快速眼动睡眠-快速眼动睡眠之间的中间期出现。这些生理微波动代表了一个重要的动态原理。这些微小波动可通过一种特殊的睡眠微分析法检测到。这种微分析表明，全身性棘波模式患者的发作与觉醒反应有关。这可能导致中间状态延长，引起发作加剧，从而形成恶性循环。
