Legros Alexandre, Beuter Anne
Department of Imaging, Lawson Health Research Institute, St. Joseph's Health Care, 268 Grosvenor Street, London, Ont., Canada N6A 4V2.
Neurotoxicology. 2006 Jul;27(4):534-46. doi: 10.1016/j.neuro.2006.02.007. Epub 2006 Apr 18.
It is becoming important to specify the smallest effects of extremely low frequency (ELF) magnetic fields (MF) on human physiology. One difficulty is that some people seem more sensitive and more responsive than others to MF exposure. Consequently, within- and between-subject differences have to be taken into account when evaluating these effects. As shown in previous work, human postural tremor is sensitive to MF exposure. But data about individual responses have not been examined in detail. Thus, postural tremor of 24 subjects was evaluated under ELF MF "on" and "off" conditions in a double-blind real/sham exposure protocol. The direction of the tremor changes was analyzed individually for three tremor characteristics. Results showed that subjects with high amplitude tremor seem to be more responsive to MF exposure. MF had an instantaneous effect (between "on" and "off" conditions) and also a more delayed and persistent one (between real and sham conditions), but differences were small. Moreover, due to the within- and between-subject variability, no statistical analysis could be done. However, these results do not show any potentially harmful effect of domestic or industrial 50 Hz MF on humans. They provide a starting point to orient future studies and should be taken into account in the establishment of new exposure limits.
明确极低频（ELF）磁场（MF）对人体生理的最小影响正变得愈发重要。一个难题在于，有些人似乎比其他人对MF暴露更为敏感且反应更强烈。因此，在评估这些影响时，必须考虑个体内部和个体之间的差异。如先前研究所示，人体姿势性震颤对MF暴露敏感。但关于个体反应的数据尚未得到详细研究。因此，在一项双盲真实/假暴露方案中，对24名受试者在ELF MF“开启”和“关闭”条件下的姿势性震颤进行了评估。针对三种震颤特征分别分析了震颤变化的方向。结果显示，震颤幅度较大的受试者似乎对MF暴露反应更强烈。MF有即时效应（在“开启”和“关闭”条件之间），也有更延迟和持久的效应（在真实和假暴露条件之间），但差异较小。此外，由于个体内部和个体之间的变异性，无法进行统计分析。然而，这些结果并未显示家用或工业用50 Hz MF对人体有任何潜在有害影响。它们为指导未来研究提供了一个起点，并且在制定新的暴露限值时应予以考虑。
