Sidman R D
Department of Mathematics, University of Southwestern Louisiana, Lafayette 70504-1010.
J Clin Neurophysiol. 1991 Oct;8(4):432-41. doi: 10.1097/00004691-199110000-00007.
Source localization techniques such as the dipole localization method (DLM) have been used to elucidate the neural origins of scalp-recorded potentials. The type of source assumed in such techniques is usually suggested by the distribution of voltage maximums and minimums in scalp topographical contour maps. Unfortunately, the physical layers between the neural generators and scalp recording sites tend to smear and attenuate the potential fields, making it impossible, in some cases, to distinguish between single and multiple sources or extended layers. In this report, a mathematical (noninvasive) technique is described for simulating the potential fields that could be recorded directly on the surface of the brain. Such "cortical" potential fields exhibit details that are not apparent in the scalp topography. In several recent publications, this cortical imaging technique (CIT) has been tested on artificial and experimental data. After describing these results, some possible applications of CIT to clinical data will be presented.
诸如偶极子定位法（DLM）之类的源定位技术已被用于阐明头皮记录电位的神经起源。此类技术中假设的源类型通常由头皮地形图中电压最大值和最小值的分布来暗示。不幸的是，神经发生器与头皮记录部位之间的物理层往往会使电位场模糊并衰减，在某些情况下，使得无法区分单个和多个源或扩展层。在本报告中，描述了一种数学（非侵入性）技术，用于模拟可直接在大脑表面记录的电位场。此类“皮质”电位场呈现出在头皮地形图中不明显的细节。在最近的几篇出版物中，这种皮质成像技术（CIT）已在人工和实验数据上进行了测试。在描述这些结果之后，将介绍CIT在临床数据中的一些可能应用。
