Tselis Nikolaos, Heyd Reinhard, Zamboglou Nikolaos
Strahlenklinik Klinikum Offenbach, Starkenburgring 66, 63069 Offenbach am Main, Germany.
Strahlenther Onkol. 2006 Apr;182(4):247-51. doi: 10.1007/s00066-006-1480-5.
A 32-year-old female patient underwent surgical synovectomy in the right distal radioulnar joint because of local recurrence of pigmented villonodular synovitis (PVNS) after previous surgery. 7 weeks after her second surgery she received fractionated radiation therapy (RT) to a total dose of 36.0 Gy given in five weekly fractions of 2.0 Gy. Apart from a mild skin erythema the patient had no early morbidity related to the use of RT. After a follow-up of 36 months no local recurrence was detected.
In accordance with literature data the hitherto course of the presented case corroborates that RT is a safe and effective treatment option for the prevention of PVNS recurrence.
一名32岁女性患者因既往手术治疗后色素沉着绒毛结节性滑膜炎（PVNS）局部复发，接受了右桡尺远侧关节滑膜切除术。第二次手术后7周，她接受了分次放射治疗（RT），总剂量为36.0 Gy，分5周给予，每周剂量为2.0 Gy。除了轻度皮肤红斑外，患者没有与放疗相关的早期并发症。随访36个月后，未发现局部复发。
根据文献数据，本病例的治疗过程证实，放疗是预防PVNS复发的一种安全有效的治疗选择。
