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消化道黏膜炎:将指南付诸实践

Alimentary mucositis: putting the guidelines into practice.

作者信息

Brennan Michael T, von Bültzingslöwen Inger, Schubert Mark M, Keefe Dorothy

机构信息

Carolinas Medical Center, Charlotte, NC, USA,

出版信息

Support Care Cancer. 2006 Jun;14(6):573-9. doi: 10.1007/s00520-006-0054-5. Epub 2006 Apr 19.

DOI:10.1007/s00520-006-0054-5
PMID:16622650
Abstract

BACKGROUND

The Mucositis Study Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology completed an evidence-based review of the literature for the management of alimentary mucositis.

DISCUSSION

The present manuscript puts these guidelines into clinical practice by presenting two cases of alimentary mucositis from cancer therapy. These cases illustrate the impact of oral and gastrointestinal mucositis on patient care.

摘要

背景

癌症支持治疗多国协会和国际口腔肿瘤学会的粘膜炎研究小组完成了一项关于消化道粘膜炎管理的循证文献综述。

讨论

本手稿通过展示两例癌症治疗引起的消化道粘膜炎病例,将这些指南应用于临床实践。这些病例说明了口腔和胃肠道粘膜炎对患者护理的影响。

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本文引用的文献

1
Palifermin for oral mucositis after intensive therapy for hematologic cancers.帕利夫明用于血液系统恶性肿瘤强化治疗后的口腔黏膜炎
N Engl J Med. 2004 Dec 16;351(25):2590-8. doi: 10.1056/NEJMoa040125.
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Recommended guidelines for the treatment of cancer treatment-induced diarrhea.癌症治疗引起的腹泻的推荐治疗指南。
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Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis.癌症治疗引起的口腔和胃肠道黏膜炎防治临床实践指南。
支持性治疗指南:价值、局限性和机遇。
Semin Oncol. 2011 Jun;38(3):367-73. doi: 10.1053/j.seminoncol.2011.03.005.
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Developing evidence-based guidelines for management of alimentary mucositis: process and pitfalls.制定循证性消化道黏膜炎管理指南:过程与陷阱
Support Care Cancer. 2006 Jun;14(6):492-8. doi: 10.1007/s00520-006-0059-0. Epub 2006 Apr 7.
5
Mucositis guidelines: what have they achieved, and where to from here?口腔黏膜炎指南:它们取得了哪些成果,未来何去何从?
Support Care Cancer. 2006 Jun;14(6):489-91. doi: 10.1007/s00520-006-0056-3. Epub 2006 Mar 30.
Cancer. 2004 May 1;100(9 Suppl):2026-46. doi: 10.1002/cncr.20163.
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Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients.癌症治疗引起的黏膜损伤的观点:发病机制、测量方法、流行病学及对患者的影响
Cancer. 2004 May 1;100(9 Suppl):1995-2025. doi: 10.1002/cncr.20162.
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The burdens of cancer therapy. Clinical and economic outcomes of chemotherapy-induced mucositis.癌症治疗的负担。化疗引起的粘膜炎的临床和经济后果。
Cancer. 2003 Oct 1;98(7):1531-9. doi: 10.1002/cncr.11671.
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Nutritional support in cancer patients.癌症患者的营养支持
JPEN J Parenter Enteral Nutr. 2002 Sep-Oct;26(5 Suppl):S63-71. doi: 10.1177/014860710202600516.
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Guidelines for the use of parenteral and enteral nutrition in adult and pediatric patients.成人及儿科患者肠外和肠内营养使用指南。
JPEN J Parenter Enteral Nutr. 2002 Jan-Feb;26(1 Suppl):1SA-138SA.
8
Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation.口腔黏膜炎与造血干细胞移植的临床及经济结局
J Clin Oncol. 2001 Apr 15;19(8):2201-5. doi: 10.1200/JCO.2001.19.8.2201.
9
Randomized trial of omeprazole or ranitidine versus placebo in the prevention of chemotherapy-induced gastroduodenal injury.奥美拉唑或雷尼替丁与安慰剂预防化疗引起的胃十二指肠损伤的随机试验。
J Clin Oncol. 2000 Feb;18(3):463-7. doi: 10.1200/JCO.2000.18.3.463.
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Misoprostol and omeprazole in the prevention of chemotherapy-induced acute gastroduodenal mucosal injury. A randomized, placebo-controlled pilot study.米索前列醇与奥美拉唑预防化疗所致急性胃十二指肠黏膜损伤:一项随机、安慰剂对照的初步研究。
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