Papadopoulos Vasilios, Tsakiridis Kosmas, Filippou Dimitrios K, Aggelopoulos Petros, Nikiforidis Dimitrios, Baltatzidis Georgios
Emergency Department, Xanthi General Hospital, Xanthi, Greece.
Rural Remote Health. 2006 Apr-Jun;6(2):505. Epub 2006 Apr 12.
Previous studies have demonstrated significant racial differences in incidence, age of onset, outcome and subsequent risk factors of stroke. However, there is scarce evidence available for Muslim populations worldwide. Xanthi region, a mainly rural and remote area in northern Greece, which is characterized by a mixed Christian/Muslim population, is considered appropriate for further studies in this area.
A prospective clinical study, based on a cohort of 530 consecutive unselected patients, 366 Christians and 164 Muslims, who had their first documented episode of stroke between 1998 and 2002. Chi-square and Fisher's exact test for comparison between discrete parameters, Student's t-test for comparison between quantitative parameters and Pearson's r for correlations (along with Bonferroni's adjustment) were used. A multiple logistic regression model was performed for evaluation of religion and gender as independent predictors of type of stroke.
Muslims, when compared with Christians: (1) present with ischemic stroke less often (p = 0.049); (2) suffer from stroke at a younger age (67.26 +/- 9.77 vs 71.43 +/- 10.88 years; p < 0.001); (3) show a significantly lower incidence rate (87.2 vs 173.9 cases/100,000 person*years; RR 1.994; p < 0.001); (4) have lower rates of diabetes (p = 0.019) and atrial fibrillation (p < 0.001) and (5) present similar mortality (p = 0.347).
Lower diabetes and atrial fibrillation rates among the Muslims of Thrace, Greece, might account for their low incidence of stroke. The contribution of culture-related habits (diet, occupation) remains to be investigated in further studies.
先前的研究已证实，中风的发病率、发病年龄、预后及后续风险因素存在显著的种族差异。然而，全球穆斯林人群的相关证据却很匮乏。希腊北部的克桑西地区主要为乡村和偏远地区，以基督教徒/穆斯林混合人口为特征，被认为适合开展该领域的进一步研究。
一项前瞻性临床研究，基于连续入选的530例未经过挑选的患者队列，其中366名基督教徒和164名穆斯林，他们在1998年至2002年间首次发生有记录的中风发作。采用卡方检验和费舍尔精确检验比较离散参数，采用学生t检验比较定量参数，采用皮尔逊相关系数r进行相关性分析（并进行邦费罗尼校正）。采用多元逻辑回归模型评估宗教信仰和性别作为中风类型的独立预测因素。
与基督教徒相比，穆斯林：（1）较少发生缺血性中风（p = 0.049）；（2）中风发病年龄较轻（67.26±9.77岁对71.43±10.88岁；p < 0.001）；（3）发病率显著较低（87.2对173.9例/100,000人·年；RR 1.994；p < 0.叭）；（4）糖尿病和心房颤动的发生率较低（p = 0.019和p < 0.001）；（5）死亡率相似（p = 0.347）。
希腊色雷斯地区穆斯林中糖尿病和心房颤动发生率较低，可能是其中风发病率低的原因。文化相关习惯（饮食、职业）的作用有待进一步研究探讨。
