Konopacki Jan, Eckersdorf Barbara, Kowalczyk Tomasz, Gołebiewski Henryk
Department of Neurobiology, The University of Lodz, Lodz 90-222, Rewolucji 1905 no. 66, Poland.
Eur J Neurosci. 2006 Apr;23(7):1811-8. doi: 10.1111/j.1460-9568.2006.04679.x.
One hundred and seven cells were recorded extracellularly in hippocampal formation (HPC) slices during carbachol-induced theta. The data obtained provided evidence of a population of HPC neurons which, when activated cholinergically, participate in the generation of in vitro theta. The activity patterns of in vitro recorded theta-related cells were shown to be similar to those of theta-related cells recorded in vivo and cells recorded in vitro during cholinergically induced theta, and non-theta intervals were successfully classified according to previously developed criteria for in vivo recorded theta-related cells. The current in vitro experiments showed that, in addition to theta-on and theta-off cells, the HPC contained cells that were probably involved in programming the appearance and duration of theta epochs and the intervals between theta epochs. These novel types of cells were termed 'gating cells'.
在卡巴胆碱诱导的θ波期间，对海马结构（HPC）切片中的107个细胞进行了细胞外记录。所获得的数据证明，有一群HPC神经元在受到胆碱能激活时会参与体外θ波的产生。体外记录的与θ波相关细胞的活动模式显示，与体内记录的与θ波相关细胞以及胆碱能诱导的θ波期间体外记录的细胞相似，并且根据先前为体内记录的与θ波相关细胞制定的标准，成功地对非θ波间隔进行了分类。当前的体外实验表明，除了θ波开启和θ波关闭细胞外，HPC还包含可能参与θ波时段的出现和持续时间以及θ波时段之间间隔编程的细胞。这些新型细胞被称为“门控细胞”。
