Chen Shui-Hu, Jen I-An, Chuang Shao-Yuan, Lin Kuan-Chia, Chou Pesus
Community Medicine Research Center and Institute of Public Health, National Yang-Ming University, 155, Li-Nong St., Sec.2, Peitou, Taipei 112, Taiwan, ROC.
Prev Med. 2006 Aug;43(2):129-35. doi: 10.1016/j.ypmed.2006.02.013. Epub 2006 Apr 19.
A community-based study was conducted to investigate summer-winter differences of component of metabolic syndrome in Kinmen, Taiwan.
A total of 8251 residents aged 40 and over were enrolled in the mass survey in Kinmen. They were investigated while on summer (July and August) and winter vacation (January and February) during 2000-2003. Demographics, physical examination findings, lifestyle variables and biochemical data were collected.
After controlling for age, body mass index, diet, lifestyle and other risk factors for component of metabolic syndrome, there were independent and significant relationships between summer-winter difference and component of metabolic syndrome. Winter season was positively correlated with blood pressure, fasting plasma glucose level, high-density lipoprotein-cholesterol (HDL-C) and waist circumference, but was negatively associated with fasting triglycerides and metabolic syndrome.
Summer season is positively associated with hypertriglyceridemia, low HDL-C and metabolic syndrome. These findings imply that cross-sectional, experimental and cohort studies of component of metabolic syndrome or metabolic syndrome should take season into account as possible confounding effects.
开展了一项基于社区的研究,以调查中国台湾金门地区代谢综合征各组分的冬夏差异。
共有8251名40岁及以上居民参与了金门地区的大规模调查。在2000年至2003年期间,于夏季(7月和8月)及寒假(1月和2月)对他们进行调查。收集了人口统计学信息、体格检查结果、生活方式变量及生化数据。
在控制了年龄、体重指数、饮食、生活方式及代谢综合征各组分的其他危险因素后,冬夏差异与代谢综合征各组分之间存在独立且显著的关系。冬季与血压、空腹血糖水平、高密度脂蛋白胆固醇(HDL-C)及腰围呈正相关,但与空腹甘油三酯及代谢综合征呈负相关。
夏季与高甘油三酯血症、低HDL-C及代谢综合征呈正相关。这些发现表明,对代谢综合征各组分或代谢综合征进行横断面、实验性及队列研究时,应考虑季节可能产生的混杂效应。