1987/1988年南非脊髓灰质炎疫情的分子流行病学

Molecular epidemiology of an outbreak of poliomyelitis in South Africa in 1987/1988.

作者信息

Tsilimigras C W, Rossouw E, Schoub B D

机构信息

Department of Virology, University of the Witwatersrand, Sandraingham, Republic of South Africa.

出版信息

J Med Virol. 1991 Oct;35(2):121-7. doi: 10.1002/jmv.1890350209.

DOI:10.1002/jmv.1890350209

PMID:1662703

Abstract

An outbreak of paralytic poliomyelitis occurred in the Republic of South Africa in 1987/88. The epidemic took place in the Natal/KwaZulu region of South Africa and was due to type 1 poliovirus. Twenty-four isolates were characterised by 1- and 2-dimensional oligonucleotide mapping and a single strain of wild-type poliovirus was identified. The same strain of virus was also isolated in other areas of South Africa at the time of the outbreak and has persisted into 1989.

摘要

1987/88年，南非共和国发生了麻痹性脊髓灰质炎疫情。该疫情发生在南非的纳塔尔/夸祖鲁地区，由1型脊髓灰质炎病毒引起。通过一维和二维寡核苷酸图谱对24株分离株进行了特征分析，鉴定出一株野生型脊髓灰质炎病毒。在疫情爆发时，南非其他地区也分离出了相同的病毒株，并且一直持续到1989年。