Langdown Andrew J, Tsai Nicholas, Auld Jason, Walsh William R, Walker Peter, Bruce Warwick J M
Department of Trauma and Orthopaedics, Portsmouth Hospitals NHS Trust, Cosham, Postmouth, UK.
J Arthroplasty. 2006 Apr;21(3):381-4. doi: 10.1016/j.arth.2005.03.032.
We have prospectively recorded ambient operating theater temperature from 186 total knee arthroplasties and the time taken for the cement to set at implantation. The majority of cases used Antibiotic Simplex cement (n = 131), and the rest, Simplex with tobramycin (n = 55). Set time was defined as when a no. 15 scalpel could not indent the cement surface at either the femoral or tibial interface. There was a reasonable negative correlation between temperature and setting time (Antibiotic Simplex: Pearson correlation coefficient, R = -0.674; Simplex with tobramycin: R = -0.655). There was also a considerable variation of setting time at any given theater temperature. There is an inverse relationship between ambient theater temperature and the setting time for Simplex cement, and surgeons should be aware that the setting time can vary considerably. Their operative protocol should take this into account.
我们前瞻性地记录了186例全膝关节置换术中手术室的环境温度以及植入时骨水泥凝固所需的时间。大多数病例使用抗生素单纯型骨水泥（n = 131），其余使用含妥布霉素的单纯型骨水泥（n = 55）。凝固时间定义为15号手术刀在股骨或胫骨界面均无法压痕骨水泥表面的时间。温度与凝固时间之间存在合理的负相关（抗生素单纯型骨水泥：皮尔逊相关系数，R = -0.674；含妥布霉素的单纯型骨水泥：R = -0.655）。在任何给定的手术室温度下，凝固时间也存在相当大的差异。手术室环境温度与单纯型骨水泥的凝固时间呈反比关系，外科医生应意识到凝固时间可能会有很大差异。他们的手术方案应考虑到这一点。
