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最佳证据主题报告。β受体阻滞剂用于可卡因诱发的急性冠状动脉综合征。

Best evidence topic report. Beta-Blockers in cocaine induced acute coronary syndrome.

作者信息

Sen Ayan, Fairbairn Tim, Levy Freya

机构信息

Manchester Royal Infirmary.

出版信息

Emerg Med J. 2006 May;23(5):401-2. doi: 10.1136/emj.2006.036582.

Abstract

A short cut review was carried out to establish whether beta blockers should be used in the treatment of chest pain associated with cocaine use. 12 papers were found, of which two presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are tabulated. The clinical bottom line is that Beta Blockers should not be used in the treatment of cocaine induced myocardial ischaemia.

摘要

进行了一项简短的综述,以确定β受体阻滞剂是否应用于治疗与可卡因使用相关的胸痛。共找到12篇论文,其中两篇提供了回答该临床问题的最佳证据。现将这些最佳论文的作者、发表日期和国家、研究的患者群体、研究类型、相关结果、结果及研究不足之处列成表格。临床要点是,β受体阻滞剂不应应用于治疗可卡因诱发的心肌缺血。

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本文引用的文献

1
Influence of labetalol on cocaine-induced coronary vasoconstriction in humans.
Am J Med. 1993 Jun;94(6):608-10. doi: 10.1016/0002-9343(93)90212-8.
2
Potentiation of cocaine-induced coronary vasoconstriction by beta-adrenergic blockade.
Ann Intern Med. 1990 Jun 15;112(12):897-903. doi: 10.7326/0003-4819-112-12-897.

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