Best evidence topic report. Cocaine induced myocardial ischaemia: nitrates versus benzodiazepines.
作者信息
Bhangoo Priya, Parfitt Andrew, Wu Tammy
机构信息
St Thomas' Hospital, London, UK.
出版信息
Emerg Med J. 2006 Jul;23(7):568-9. doi: 10.1136/emj.2006.038497.
Abstract
A short cut review was carried out to establish whether nitrates are better than benzodiazepines in the treatment of cocaine induced chest pain. Seven citations were reviewed of which two answered the three part question. The clinical bottom line is that in patients with cocaine induced chest pain it appears that nitrates or benzodiazepines are effective in combination or alone in resolving chest pain and improving cardiac performance. We recommend that the agent of choice may be influenced by the presence or absence of concurrent CNS symptoms.
摘要
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本文引用的文献
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A prospective, randomized, controlled trial of benzodiazepines and nitroglycerine or nitroglycerine alone in the treatment of cocaine-associated acute coronary syndromes.
Am J Emerg Med. 2003 Jan;21(1):39-42. doi: 10.1053/ajem.2003.50010.
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Randomized, double-blind, placebo-controlled trial of diazepam, nitroglycerin, or both for treatment of patients with potential cocaine-associated acute coronary syndromes.
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