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[手术治疗伴有纵隔淋巴结转移(N2)的肺癌]

[Surgery in the treatment of pulmonary carcinoma with mediastinal lymph node metastasis (N2)].

作者信息

Quidaciolu F, Cappato S, Pastorino G, Guasone F, De Negri A, Giua R

机构信息

Ospedali di Genova-Sampierdarena, Regione Liguria-U.S.L. n. 11.

出版信息

Minerva Chir. 1991 Oct 31;46(20):1105-8.

PMID:1662787
Abstract

This study is based on the analysis of the survival data in patients with N2 disease reported by Martini, Pearson, Shields et al. Many factors appear to influence survival of this group of patients. We made a retrospective analysis of a series of 91 patients with N2 disease between January 1980 and March 1985. Sixty-nine patients (71.5%) presented clinically N2 disease; 44 patients (63.7%) were treated with complete resection and postoperative irradiation, the actuarial five year survival was 11%. Twenty-two patients (24.2%) were discovered to have N2 disease at thoracotomy. Twenty-one patients underwent resection and the actuarial five year survival was 29%. We conclude that surgery can be effective in a highly selective group of patients.

摘要

本研究基于对Martini、Pearson、Shields等人报告的N2期疾病患者生存数据的分析。许多因素似乎会影响这组患者的生存情况。我们对1980年1月至1985年3月期间的91例N2期疾病患者进行了回顾性分析。69例患者(71.5%)临床上表现为N2期疾病;44例患者(63.7%)接受了根治性切除及术后放疗,精算5年生存率为11%。22例患者(24.2%)在开胸手术时被发现患有N2期疾病。21例患者接受了切除术,精算5年生存率为29%。我们得出结论,手术对高度选择的一组患者可能有效。

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