Zhu M, Collins M J, Iskander D R
Contact Lens and Visual Optics Laboratory, School of Optometry, Queensland University of Technology, Kelvin Grove, Australia.
Eye (Lond). 2007 May;21(5):624-32. doi: 10.1038/sj.eye.6702293. Epub 2006 Apr 21.
To investigate fluctuations in the ocular surface, we used high-speed videokeratoscopy (50 Hz) to measure the dynamics of the ocular surface topography.
Ocular surface height difference maps were computed to illustrate the changes in the tear film in the inter-blink interval. Topography data were used to derive the ocular surface wavefront aberrations up to the fourth radial order of the Zernike polynomial expansion. We examined the ocular surface dynamics and temporal changes in the ocular surface wavefront aberrations in the inter-blink interval.
During the first 0.5 s following a blink, the ocular surface height at the upper edge of the topography map increased by about 2 mum. Temporal changes occurred for some ocular surface wavefront aberrations and appeared to be related to changes in the distribution of tear film.
In the clinical measurement of ocular surface topography using videokeratoscopy or optics of the eye using wavefront sensors, care should be taken to avoid the initial tear film build-up phase following a blink to achieve more consistent results.
为了研究眼表的波动情况，我们使用高速角膜地形图仪（50赫兹）来测量眼表地形的动态变化。
计算眼表高度差图以说明眨眼间隔期泪膜的变化。利用地形数据得出直至泽尼克多项式展开式第四径向阶的眼表波前像差。我们研究了眨眼间隔期眼表的动态变化以及眼表波前像差的时间变化。
在眨眼后的最初0.5秒内，地形图上边缘处的眼表高度增加了约2微米。一些眼表波前像差出现了时间变化，且似乎与泪膜分布的变化有关。
在使用角膜地形图仪进行眼表地形的临床测量或使用波前传感器进行眼睛光学测量时，应注意避免眨眼后的初始泪膜形成阶段，以获得更一致的结果。
