使用二维信号强度图数据可视化技术检测液相色谱/质谱数据中的伪峰和肽修饰。
Detection of artifacts and peptide modifications in liquid chromatography/mass spectrometry data using two-dimensional signal intensity map data visualization.
作者信息
Berg Matthias, Parbel Axel, Pettersen Harald, Fenyö David, Björkesten Lennart
机构信息
GE Healthcare, Oskar Schlemmer Str. 11, D-80807 München, Germany.
出版信息
Rapid Commun Mass Spectrom. 2006;20(10):1558-62. doi: 10.1002/rcm.2476.
DOI:10.1002/rcm.2476
PMID:16628601
Abstract
We demonstrate how visualization of liquid chromatography/mass spectrometry data as a two-dimensional signal intensity map can be used to assess the overall quality of the data, for the identification of polymer contaminants and artifacts, as well as for the confirmation of post-translational modifications.
摘要
我们展示了如何将液相色谱/质谱数据可视化为二维信号强度图，以评估数据的整体质量、识别聚合物污染物和伪像，以及确认翻译后修饰。
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