Tan E K, Chan L L
Department of Neurology, Singapore, General Hospital, Singapore.
Acta Neurol Scand. 2006 May;113(5):350-2. doi: 10.1111/j.1600-0404.2006.00581.x.
Case reports of co-existent Parkinson's disease (PD) and hemifacial spasm (HFS) suggest that there may be a relationship between these conditions. Three of 300 (1%) PD patients presented with HFS compared with 0/300 (0%) controls. The mean age of the three PD patients with HFS was 68.7 +/- 8.0 (60-76) years, with the majority having left-sided HFS. All three patients developed HFS symptoms at around the onset of PD and they were significantly older than the 100 patients with HFS alone (P < 0.05). Our study demonstrated no significant increased risk of HFS amongst the general PD population and hence HFS symptoms are unlikely to be of clinical importance for most PD patients.
帕金森病（PD）与半面痉挛（HFS）并存的病例报告表明，这些病症之间可能存在关联。300例PD患者中有3例（1%）出现HFS，而对照组300例中则为0例（0%）。3例患有HFS的PD患者的平均年龄为68.7±8.0（60 - 76）岁，大多数为左侧HFS。所有3例患者均在PD发病前后出现HFS症状，且他们明显比100例单纯患有HFS的患者年龄更大（P < 0.05）。我们的研究表明，在一般PD人群中，HFS的风险没有显著增加，因此对于大多数PD患者来说，HFS症状不太可能具有临床重要性。
