Shack L G, Wood H E, Kang J Y, Brewster D H, Quinn M J, Maxwell J D, Majeed A
Scottish Cancer Registry, Information & Statistics Division, Edinburgh, UK.
Aliment Pharmacol Ther. 2006 May 1;23(9):1297-306. doi: 10.1111/j.1365-2036.2006.02891.x.
Time trends in mortality from small intestinal cancer have not been studied for the 1990s.
To examine secular trends in incidence of, mortality from, and survival from, small intestinal cancer in England & Wales and Scotland from 1975 to 2002, considering also histological type (incidence), subsite (incidence) and indices of social deprivation (incidence and survival).
Data were extracted from the Scottish Cancer Registry database and the General Register Office for Scotland, and from the National Cancer Intelligence Centre at the Office for National Statistics for England & Wales.
Incidence rates for small intestinal cancer increased for both England & Wales and Scotland over the study period. They were highest among older individuals and generally greater for males than for females. Despite the increase in incidence rates, mortality rates from small intestinal tumours tended to remain stable over the study period, and the general trend was towards increasing survival. Indices of social deprivation were not obviously related to the incidence of small intestinal cancer and did not influence survival.
Incidence rates for small intestinal cancer for both England & Wales and Scotland increased in the last quarter of the 20th century, but survival rates improved and mortality rates declined.
20世纪90年代小肠癌死亡率的时间趋势尚未得到研究。
研究1975年至2002年英格兰和威尔士以及苏格兰小肠癌的发病率、死亡率和生存率的长期趋势，同时考虑组织学类型（发病率）、亚部位（发病率）和社会剥夺指数（发病率和生存率）。
数据从苏格兰癌症登记数据库和苏格兰总登记处，以及英格兰和威尔士国家统计局的国家癌症情报中心提取。
在研究期间，英格兰和威尔士以及苏格兰的小肠癌发病率均有所上升。发病率在老年人中最高，总体上男性高于女性。尽管发病率有所上升，但小肠肿瘤的死亡率在研究期间趋于稳定，总体趋势是生存率提高。社会剥夺指数与小肠癌发病率没有明显关联，也不影响生存率。
20世纪最后25年，英格兰和威尔士以及苏格兰的小肠癌发病率均有所上升，但生存率提高，死亡率下降。
