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重度新生儿肺动脉高压的联合药物治疗

Combination pharmacotherapy for severe neonatal pulmonary hypertension.

作者信息

Filan Peter M, McDougall Peter N, Shekerdemian Lara S

机构信息

Department of Neonatology, Royal Children's Hospital, Melbourne, Australia.

出版信息

J Paediatr Child Health. 2006 Apr;42(4):219-20. doi: 10.1111/j.1440-1754.2006.00835.x.

Abstract

Pulmonary hypertension can complicate the early clinical course in newborn infants with congenital diaphragmatic hernia. We report the successful use of combination therapy with enteral sildenafil and intravenous prostaglandin E1 in a preterm infant with severe pulmonary hypertension and right heart failure early after congenital diaphragmatic hernia repair.

摘要

肺动脉高压可使先天性膈疝新生儿的早期临床病程复杂化。我们报告了在1例先天性膈疝修补术后早期出现严重肺动脉高压和右心衰竭的早产儿中,成功联合使用肠内西地那非和静脉注射前列腺素E1进行治疗的病例。

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