de Jong Ritske, Gladwin Thomas E, 't Hart Bernard M
Department of Psychology, School for Behavioral and Cognitive Neurosciences, University of Groningen, Groningen, The Netherlands.
Brain Res. 2006 Aug 11;1105(1):73-82. doi: 10.1016/j.brainres.2006.03.030. Epub 2006 Apr 21.
Lateralized readiness potential (LRP) and time-frequency domain LRP-type measures, called motor-related amplitude asymmetries (MRAA), in the mu band (9-13 Hz; mu-MRAA) and the beta band (18-26 Hz; beta-MRAA) were used to study the time course of preparation in a task-switching task and a response precuing task. Several dissociations between LRP and mu-MRAA and beta-MRAA were found. Mu-MRAA and beta-MRAA, but not LRP, exhibited an early and strong reversal in cortical lateralization when advance preparation for a switch of response hand was required. LRP, but not mu-MRAA or beta-MRAA, was sensitive to manipulation of the probability that advance preparation of response hand would be useful in a response precuing task. These dissociations replicate earlier findings and suggest that movement-related cortical rhythms and cortical potentials are associated with distinct preparatory component processes that differ in terms of level of abstraction and effort, in line with similar functional distinctions between component processes underlying executive control in task switching. This suggests that a fine-grained analysis of subprocesses involved in motor control may provide important guiding principles for the study and understanding of levels and mechanisms of cognitive control.
在一项任务切换任务和一项反应预提示任务中，使用了偏侧化准备电位（LRP）以及在μ频段（9 - 13赫兹；μ-MRAA）和β频段（18 - 26赫兹；β-MRAA）中被称为运动相关振幅不对称（MRAA）的时频域LRP型测量方法，来研究准备过程的时间进程。研究发现LRP与μ-MRAA和β-MRAA之间存在多种分离现象。当需要提前准备切换反应手时，μ-MRAA和β-MRAA表现出早期且强烈的皮质侧化反转，但LRP没有。在反应预提示任务中，LRP对反应手提前准备是否有用的概率操纵敏感，而μ-MRAA和β-MRAA则不敏感。这些分离现象重复了早期的研究结果，并表明与运动相关的皮质节律和皮质电位与不同的准备成分过程相关，这些过程在抽象水平和努力程度方面存在差异，这与任务切换中执行控制所涉及的成分过程之间的类似功能差异一致。这表明对运动控制中涉及的子过程进行细粒度分析，可能为研究和理解认知控制的水平及机制提供重要的指导原则。
