Kuendgen Andrea, Matsuda Akira, Germing Ulrich
Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany.
Leuk Res. 2007 Jan;31(1):103-4. doi: 10.1016/j.leukres.2006.03.007. Epub 2006 Apr 19.
Myelodysplastic syndromes show ethnic differences. Several investigators have reported a striking difference in age at diagnosis between Eastern and Western MDS patients. Referring to a letter bei Paydas speculating about toxic environmental influences as a possible cause for younger age in Asian MDS patients, we discuss our experience from a direct comparison of Japanese and German MDS, in particular refractory anemia patients.
骨髓增生异常综合征存在种族差异。几位研究者报告称，东西方骨髓增生异常综合征患者的诊断年龄存在显著差异。针对Paydas的一封信中推测有毒环境影响可能是亚洲骨髓增生异常综合征患者年龄较轻的原因，我们讨论了对日本和德国骨髓增生异常综合征患者，尤其是难治性贫血患者进行直接比较的经验。
