在一例慢性人工晶状体眼内炎患者中，通过聚合酶链反应检测到来自植入的人工晶状体的痤疮丙酸杆菌DNA。
Propionibacterium acnes DNA from an explanted intraocular lens detected by polymerase chain reaction in a case of chronic pseudophakic endophthalmitis.
作者信息
Lai Jui-Yang, Chen Ko-Hua, Lin Ying-Cheng, Hsu Wen-Ming, Lee Shui-Mei
机构信息
Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan, China.
出版信息
J Cataract Refract Surg. 2006 Mar;32(3):522-5. doi: 10.1016/j.jcrs.2005.12.071.
We report a case of Propionibacterium acnes DNA from the explanted intraocular lens (IOL) a 76-year-old man with delayed-onset chronic endophthalmitis. The detection was by polymerase chain reaction (PCR). Slitlamp microscopic examination showed cells and flare in the anterior chamber, keratic precipitates on the endothelium, and multiple white plaques on both surfaces of the IOL. Propionibacterium acnes DNA was found in both the aqueous humor and the explanted IOL by PCR. Scanning electron microscopy showed diphtheroid particles, a coating of biofilm-like deposits, as well as scattered crystals on the surface of the explanted IOL and supported the possibility of P acne colonies on the IOL.
我们报告了一例从一位76岁患有迟发性慢性眼内炎男性患者的植入人工晶状体（IOL）中检测到痤疮丙酸杆菌DNA的病例。检测方法为聚合酶链反应（PCR）。裂隙灯显微镜检查显示前房有细胞和闪光，内皮有角膜后沉着物，IOL两面有多个白色斑块。通过PCR在房水和植入的IOL中均发现了痤疮丙酸杆菌DNA。扫描电子显微镜显示，在植入的IOL表面有类白喉颗粒、生物膜样沉积物涂层以及散在的晶体，支持IOL上存在痤疮丙酸杆菌菌落的可能性。
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