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西班牙裔青少年血液透析患者的治疗结果:终末期肾病临床绩效指标项目的研究发现

Outcomes for adolescent Hispanic hemodialysis patients: findings from the ESRD Clinical Performance Measures Project.

作者信息

Frankenfield Diane L, Atkinson Meredith A, Fivush Barbara A, Neu Alicia M

机构信息

Centers for Medicare & Medicaid Services, Office of Clinical Standards and Quality, Baltimore, MD, USA.

出版信息

Am J Kidney Dis. 2006 May;47(5):870-8. doi: 10.1053/j.ajkd.2006.01.021.

Abstract

BACKGROUND

There is limited information regarding outcomes of dialytic care for Hispanic adolescent hemodialysis patients.

METHODS

Ethnicity information was collected for all adolescent in-center hemodialysis patients for the Centers for Medicare & Medicaid Services 2000 End-Stage Renal Disease (ESRD) Clinical Performance Measures Project. Associations between intermediate outcomes and Hispanic ethnicity were determined. Associations of ethnicity and other demographic/clinical variables with hospitalization and transplantation during the 12-month follow-up period were examined.

RESULTS

Twenty-two percent of patients were identified as Hispanic; 40%, as non-Hispanic black; and 32%, as non-Hispanic white. Hispanic patients were younger and more likely to have congenital/urological causes of ESRD. More Hispanic patients had a mean single-pool Kt/V of 1.2 or greater compared with non-Hispanic blacks and non-Hispanic whites (87% versus 73% and 79%; P = 0.036). More Hispanic patients had a mean serum albumin level of 3.5/3.2 g/dL (bromcresol green/bromcresol purple method) or greater (> or = 35/32 g/L; 91% versus 82% and 76%; P = 0.017). More Hispanic patients compared with non-Hispanic blacks and non-Hispanic whites were dialyzed with a catheter for 90 days or longer (30% versus 21% and 23%; P = 0.027). In the final multivariate Cox proportional hazard models, Hispanic patients were at a slightly decreased risk for hospitalization compared with non-Hispanics (adjusted hazard ratio [adjHR], 0.63; P = 0.031) and were as likely to undergo a first transplantation as non-Hispanic whites (adjHR, 0.56; P = 0.099).

CONCLUSION

Adolescent Hispanic hemodialysis patients experience equivalent or better intermediate outcomes of dialytic care than non-Hispanics. They experienced a decreased risk for subsequent hospitalization and are as likely to undergo transplantation within 12 months as non-Hispanic whites.

摘要

背景

关于西班牙裔青少年血液透析患者的透析治疗结果的信息有限。

方法

为医疗保险和医疗补助服务中心2000年终末期肾病(ESRD)临床绩效指标项目收集了所有青少年中心血液透析患者的种族信息。确定了中间结果与西班牙裔种族之间的关联。研究了种族和其他人口统计学/临床变量与12个月随访期内住院和移植之间的关联。

结果

22%的患者被确定为西班牙裔;40%为非西班牙裔黑人;32%为非西班牙裔白人。西班牙裔患者更年轻,更有可能因先天性/泌尿系统原因导致ESRD。与非西班牙裔黑人和非西班牙裔白人相比,更多西班牙裔患者的平均单池Kt/V为1.2或更高(87%对73%和79%;P = 0.036)。更多西班牙裔患者的平均血清白蛋白水平为3.5/3.2 g/dL(溴甲酚绿/溴甲酚紫法)或更高(≥35/32 g/L;91%对82%和76%;P = 0.017)。与非西班牙裔黑人和非西班牙裔白人相比,更多西班牙裔患者使用导管透析90天或更长时间(30%对21%和23%;P = 0.027)。在最终的多变量Cox比例风险模型中,与非西班牙裔相比,西班牙裔患者住院风险略有降低(调整后风险比[adjHR],0.63;P = 0.031),并且与非西班牙裔白人进行首次移植的可能性相同(adjHR,0.56;P = 0.099)。

结论

西班牙裔青少年血液透析患者的透析治疗中间结果与非西班牙裔相当或更好。他们随后住院的风险降低,并且在12个月内接受移植的可能性与非西班牙裔白人相同。

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